Hostname: page-component-6766d58669-kn6lq Total loading time: 0 Render date: 2026-05-21T22:50:27.959Z Has data issue: false hasContentIssue false
  • English
  • Français

Rosai-Dorfman disease presenting as a parotid mass

Published online by Cambridge University Press:  29 June 2007

L. Norman ,
A. C. Bateman ,
G. W. R. Watters ,
V. Singh  and
A. V. Spedding
L. Norman
Affiliation:
Department of Otolaryngology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
A. C. Bateman*
Affiliation:
Department of Histopathology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
G. W. R. Watters
Affiliation:
Department of Otolaryngology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
V. Singh
Affiliation:
Department of Otolaryngology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
A. V. Spedding
Affiliation:
Department of Histopathology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
*
Address for correspondence: Dr A. C. Bateman, Department of Histopathology, Level E, South Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD. Fax: 01703 796869
Get access Rights & Permissions [Opens in a new window]

Abstract

Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare, benign disease of unknown aetiology. This disease typically presents with massive, painless cervical lymphadenopathy but may occur in a wide variety of extranodal sites. Our report describes a 71-year-old man who presented with a discrete, unilateral parotid mass which was clinically suggestive of a primary salivary gland tumour. Initial cytological examination of a fine needle aspirate specimen taken from the mass demonstrated a discohesive cell population with nuclear atypia, raising the possibility of malignancy. However, excision of the mass and histological examination enabled a definitive diagnosis to be made.

Keywords

Histiocytosis, sinusLymph nodeNeck

Information

Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 11 , November 1997 , pp. 1091 - 1093
Copyright
Copyright © JLO (1984) Limited 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Foucar, E., Rosai, J., Dorfman, R. F. (1990) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): review of the entity. Seminars in Diagnostic Pathology 7: 19–73.Google ScholarPubMed
Goodnight, J. W., Wang, M. B., Sercarz, J. A., Fu, Y. S. (1996) Extranodal Rosai-Dorfman Disease of the head and neck. Laryngoscope 106: 253–256.Google Scholar
Hammond, L. A., Keh, C., Rowlands, D. C. (1996) Rosai-Dorfman disease in the breast. Histopathology 29: 582–584.CrossRefGoogle ScholarPubMed
Horneff, G., Jurgens, H., Hort, W., Karitzy, D., Gobel, U. (1996) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): response to methotrexate and mercaptopurine. Medical and Pediatric Oncology 27: 187–192.Google Scholar
Komp, D. M. (1990) The treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Seminars in Diagnostic Pathology 7: 83–86.Google ScholarPubMed
Levine, P. H., Jahan, N., Murari, P., Manak, M., Jaffe, E. S. (1992) Detection of human herpesvirus 6 in tissues involved by sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease). Journal of Infectious Diseases 166: 291–295.CrossRefGoogle ScholarPubMed
McAlister, W. H., Herman, T., Dehner, L. P. (1990) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorf-man Disease). Paediatric Radiology 20: 425–432.CrossRefGoogle ScholarPubMed
Naidu, R. K., Urken, M. L., Som, P. M., Danon, A., Biller, H. F. (1990) Extranodal head and neck sinus histiocytosis with massive lymphadenopathy. Otolaryngology – Head and Neck Surgery 102: 764–767.Google Scholar
Rosai, J., Dorfman, R. F. (1969) Sinus Histiocytosis with massive lymphadenopathy: a newly recognised benign clinicopathological entity. Archives of Pathology 87: 63–70.Google ScholarPubMed
Rosai, J., Dorfman, R. F. (1972) Sinus histiocytosis with massive lymphadenopathy: A pseudolymphomatous benign disorder. Analysis of 34 cases. Cancer 30: 1174–1188.Google Scholar
Trautman, B. C., Stanley, M. W., Goding, G. S., Rosai, J. (1991) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): diagnosis by fine needle aspiration. Diagnostic Cytopathology 7: 513–516.Google Scholar