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Development and implementation of the Forge AHEAD Center: A collaborative research center addressing cardiometabolic disease through academic–community partnership in the Deep South

Published online by Cambridge University Press:  06 May 2026

Gareth R. Dutton
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Monica L. Baskin
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Orlando M. Gutiérrez
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Caroline E. Compretta
Affiliation:
University of Mississippi Medical Center, Jackson, USA
Michael J. Mugavero
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
April A. Agne
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Lauren Hebert-Henderson
Affiliation:
Independent scholar
Trudi V. Horton
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Rikki M. Tanner
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
April P. Carson
Affiliation:
University of Mississippi Medical Center, Jackson, USA
Peter T. Katzmarzyk
Affiliation:
Pennington Biomedical Research Center, USA
Timothy Turner
Affiliation:
Tuskegee University, USA
Tapan S. Mehta
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Kara D. Denstel
Affiliation:
Pennington Biomedical Research Center, USA
Aseel El Zein
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Michael E. Hall
Affiliation:
University of Mississippi Medical Center, Jackson, USA
Sharonda Hardy
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
Eboni Price-Haywood
Affiliation:
Ochsner Xavier Institute for Health Equity and Research, USA
Andrea L. Cherrington*
Affiliation:
The University of Alabama at Birmingham Heersink School of Medicine , USA
*
Corresponding author: A.L. Cherrington; Email: acherrington@uabmc.edu
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Abstract

The Deep South has the highest rates of obesity, diabetes, and hypertension in the nation, with marked disparities by race, socioeconomic status, and rurality. The mission of the Forge AHEAD Center is to improve health outcomes and reduce the burden of cardiometabolic diseases across the Deep South, with a particular focus on the prevention and treatment of these chronic diseases. Forge AHEAD is unified thematically by its application of a precision public health approach across the care continuum, defined as delivering the right intervention to the right population at the right time. This approach acknowledges the importance of context and individual beliefs and preferences, as well as the need for multi-level and multi-domain interventions to achieve health improvements. The Center brings together an interdisciplinary team of investigators from 4 institutions in 3 contiguous states in the region, as well as non-academic partners to extend cardiometabolic research into real-world community and clinical settings. Given the high prevalence of cardiometabolic diseases in the Deep South and the strong research base of the partnering institutions, the Forge AHEAD Center is ideally situated to inform research, clinical care, and policy to improve health outcomes in a region of substantial need.

Information

Type
Special Communication
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use and/or adaptation of the article.
Copyright
© The Author(s), 2026. Published by Cambridge University Press on behalf of Association for Clinical and Translational Science
Figure 0

Figure 1. Figure 1 long description.Conceptual framework for the application of the precision public health approach at multiple levels of the socio-ecologic framework and across the care continuum.

Figure 1

Figure 2. Figure 2 long description.Administrative structure of the Forge AHEAD Center.

Figure 2

Table 1. Center evaluation metricsTable 1 long description.

Figure 3

Figure 3. Figure 3 long description.Forge AHEAD Center mission, vision, and values.