Hostname: page-component-89b8bd64d-ktprf Total loading time: 0 Render date: 2026-05-08T02:43:49.699Z Has data issue: false hasContentIssue false

Impact of young adult life transitions on adult mental health problems: a propensity score analysis

Published online by Cambridge University Press:  19 May 2025

William E. Copeland*
Affiliation:
Department of Psychiatry, University of Vermont, Burlington, VT, USA
Shania Prytherch
Affiliation:
Department of Psychiatry, University of Vermont, Burlington, VT, USA
W. Rothenberg
Affiliation:
Center for Child and Family Policy, Duke University, Durham, NC, USA
Jennifer W. Godwin
Affiliation:
Center for Child and Family Policy, Duke University, Durham, NC, USA
Lauren Gaydosh
Affiliation:
Sociology Department, University of North Carolina, Chapel Hill, NC, USA
Iliya Gutin
Affiliation:
Sociology Department, University of North Carolina, Chapel Hill, NC, USA Center of Policy Research, Syracuse University, Syracuse, NY, USA
Guangyu Tong
Affiliation:
Cardiovascular Medicine, Yale University, New Haven, CT, USA
Lilly Shanahan
Affiliation:
Department of Psychology, University of Zurich, Zurich, Switzerland
*
Corresponding author: William E. Copeland; Email: william.copeland@med.uvm.edu
Rights & Permissions [Opens in a new window]

Abstract

Background

Mental health problems commonly persist from childhood to adulthood. This study tested whether young adult life transitions can improve adult mental health symptoms after adjusting for childhood mental health symptoms.

Methods

The analysis uses data from the prospective, representative Great Smoky Mountains Study. Life transitions (e.g., high school completion, partnering, parenthood, and living independently) were assessed up to three times in young adulthood (ages 18 to 26; 3,241 observations). A cumulative variable counted the number of young adult transitions. Emotional, substance use, and antisocial personality symptoms were assessed at age 30 (1,154 participants or 81.2% of the original sample). Propensity models adjusted for early life adversities and psychiatric symptoms.

Results

Multiple young adult transitions were common (m = 4.62; SD = 1.57). After adjusting for childhood mental health problems and adversities, each additional transition was significantly associated with a reduction in subsequent adult emotional symptoms (β = −0.34, 95% CI: −0.59, −0.08, p = 0.01) and adult antisocial personality disorder symptoms (β = −0.08, 95% CI: −0.14, −0.02, p < 0.001. These associations were stronger in males than in females. Young adult transitions were not associated with reductions in subsequent substance use symptoms (β = −0.04; 95% CI: −0.11, 0.03, p = 0.30). Young adult transitions related to educational milestones and consistent employment were associated with the largest reductions in symptoms.

Conclusions

In this cohort study, life transitions during young adulthood were associated with reduced emotional and behavioral symptoms in adulthood. These transitions may constitute a potential mental health turning point and a specific, modifiable target for social policies.

Information

Type
Original Article
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press
Figure 0

Table 1. Description of young adult positive transitions

Figure 1

Table 2. Spearman weighted and unweighted correlations for covariates with and without inverse probability of treatment weights from propensity score modeling

Figure 2

Figure 1. Average treatment effect of life transitions for emotional, antisocial personality, and substance-related psychiatric symptoms in adulthood for (a) the overall sample, (b) Males, (c) Females.

Figure 3

Figure 2. Dose–response relationship between number of life transitions and adult emotional, antisocial personality, and substance-use-related psychiatric symptoms.

Figure 4

Table 3. Associations of each individual positive transition with adult emotional, antisocial, and substance-related symptoms

Supplementary material: File

Copeland et al. supplementary material

Copeland et al. supplementary material
Download Copeland et al. supplementary material(File)
File 453.7 KB