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Inattention and Hyperactivity-Impulsivity: Psychobiological and Evolutionary Underpinnings of ADHD

Published online by Cambridge University Press:  07 November 2014

Dan J. Stein ,
Jin Fan ,
John Fossella  and
Vivienne A. Russell
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Abstract

Attention-deficit/hyperactivity disorder is a prevalent and disabling disorder that is characterized by inattention and/or hyperactivity-impulsivity, impairment in executive functions, structural and functional abnormalities in frontal-striatal circuitry, associations with particular catecholamine gene variants, and responsiveness to dopaminergic and noradrenergic agents. There is a growing integration of findings from basic and clinical studies, of data from different methods (eg, genetics and imaging), and of empirical data with hypotheses drawn from evolutionary thinking. Here we briefly summarize work on the cognitive-affective neuroscience of attention-deficit/hyperactivity disorder.

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Type
Pearls in Clinical Neuroscience
Information
CNS Spectrums , Volume 12 , Issue 3 , March 2007 , pp. 190 - 196
Copyright
Copyright © Cambridge University Press 2007

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