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Carcinoma of the maxillary antrum treated by pre-operative radiotherapy or radical radiotherapy alone

Published online by Cambridge University Press:  29 June 2007

A. J. Neal ,
F. Habib  and
H. F. Hope-Stone
A. J. Neal*
Affiliation:
Department of Radiotherapy, The Royal London Hospital, Whitechapel, London.
F. Habib
Affiliation:
Department of Radiotherapy, The Royal London Hospital, Whitechapel, London.
H. F. Hope-Stone
Affiliation:
Department of Radiotherapy, The Royal London Hospital, Whitechapel, London.
*
Dr A. J. Neal, Department of Radiotherapy, The Royal London Hospital, Whitechapel, London E1 1BB.
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Abstract

The results of pre-operative radical radiotherapy and subsequent maxillary resection are reported in 54 consecutive patients with carcinoma of the maxillary antrum treated at The Royal London Hospital from 1965 to 1989. The actuarial two and five year survivals were 50.3 per cent and 38.5 per cent respectively. Patients with adenocarcinomas fared better when compared with squamous and undifferentiated carcinomas (log rank p = <0.01). Undifferentiated carcinoma and involved regional lymph nodes were both very poor prognostic factors. In those patients who were either unfit for or refused maxillary resection, radical radiotherapy alone was still an effective treatment, with only a slight disadvantage in terms of local control and survival.

Keywords

Maxillary antrum neoplasmsradiotherapy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 12 , December 1992 , pp. 1063 - 1066
Copyright
Copyright © JLO (1984) Limited 1992

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References

Ahmad, K., Cordoba, R. B., Fayos, J. V. (1981) Squamous cell carcinoma of the maxillary sinus. Archives of Otolaryngology, 107: 48–51.CrossRefGoogle ScholarPubMed
Barley, V. L., Ellis, R.Paine, C. H. (1976) Carcinoma of the maxillary antrum. Proceedings of the Royal Society of Medicine, 69: 697–700.CrossRefGoogle ScholarPubMed
Boone, M. L. M., Harte, T. S., Higholt, H. W., Fletcher, G. H. (1968) Malignant disease of the paranasal sinuses and nasal cavity. American Journal of Rontgenology, 102: 627–636.CrossRefGoogle ScholarPubMed
Cheng, V. S. T.Wang, C. C. (1977) Carcinomas of the paranasal sinuses. Cancer, 40: 3038–3041.3.0.CO;2-9>CrossRefGoogle ScholarPubMed
Frich, J. C. (1982) Treatment of advanced carcinoma of the maxillary sinus by irradiation. International Journal of Radiation, Oncology, Biology and Physics, 8: 1453–1459.CrossRefGoogle ScholarPubMed
Harrison, D. F. N. (1973) The management of malignant tumours affecting the maxillary and ethmoidal sinuses. Journal of Laryngology and Otology, 87: 749–772.CrossRefGoogle ScholarPubMed
International Union Against Cancer (1987) In: TNM classification of malignant tumours. 4th edition, Springer-Verlag, Berlin, p 27–29.Google Scholar
Knegt, P. P., De Jong, P. C.Van Andel, J. G., Maarten, F., De Boe, F., Eykenboom, W., Van Der Schans, E. (1985) Carcinoma of the paranasal sinuses. Cancer, 56: 57–62.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Kondo, M., Ogawa, K., Inuyama, Y., Yamashita, S., Tominaga, S., Shigematsu, M., Nishiguchi, I., Hashimoto, S. (1985) Prognostic factors influencing relapse of squamous cell carcinoma of the maxillary sinus. Cancer, 55: 190–196.3.0.CO;2-2>CrossRefGoogle ScholarPubMed
Kurohara, S., Webster, J. H., Ellis, F., Fitzgerald, J. P., Shedd, D. P., Badib, A. O. (1972) Role of radiation therapy and surgery in the management of epidermoid carcinoma of the maxillary sinus. American Journal of Rontgenology, 114: 35–42.Google ScholarPubMed
Lederman, M. (1969) The treatment of tumours of the upper jaw. British Journal of Radiology, 42: 561–581.CrossRefGoogle ScholarPubMed
Lindeman, P., Eklund, U., Petruson, B. (1987) Survival after surgical treatment in maxillary neoplasms of epithelial origin. Journal of Laryngology and Otology, 101: 564–568.CrossRefGoogle ScholarPubMed
Logue, J. P., Slevin, N. J. (1991) Carcinoma of the nasal cavity and paranasal sinuses: an analysis of radical radiotherapy. Clinical Oncology, 3: 84–89.CrossRefGoogle ScholarPubMed
Pezner, R. D., Moss, W. T. (1979) Cervical lymph node metastases in patients with squamous cell carcinoma of the maxillary antrum: the role of elective irradiation of the clinically negative neck. International Journal of Radiation, Oncology, Biology and Physics, 5: 1977–1980.CrossRefGoogle ScholarPubMed
Robin, P. E., Powell, J. (1980) Regional node involvement and distant metastases in carcinoma of the nasal cavity and paranasal sinuses. Journal of Laryngology and Otology, 94: 301–309.CrossRefGoogle ScholarPubMed
Sakai, S., Fuchihata, M.Hamasaki, Y. (1976) Treatment policy for maxillary sinus carcinoma. Acta Otolaryngologica, 82: 172–181.CrossRefGoogle ScholarPubMed
Sakai, S., Hohki, A., Fuchihata, D., Tanaka, Y. (1983) Multidisciplinary treatment of maxillary sinus carcinoma. Cancer, 52: 1360–1364.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Saunders, S. H., Ruff, T. (1976) Adenocarcinoma of the paranasal sinuses. Journal of Laryngology and Otology, 90: 157–166.CrossRefGoogle Scholar
Shibuya, H., Horiuchi, J., Suzuki, S., Shioda, S., Enomoto, S. (1984) Maxillary sinus carcinoma: result of radiation therapy. International Journal of Radiation, Oncology, Biology and Physics, 10: 1021–1026.CrossRefGoogle ScholarPubMed
Tabb, H. G., Barranco, S. J. (1971) Cancer of the maxillary sinus. Larynoscope, 81: 818–827.CrossRefGoogle ScholarPubMed
Weymuller, E. A., Rearden, E. J., Nash, D. (1980) A comparison of treatment modalities in carcinoma of the maxillary antrum. Archives of Otolaryngology, 106: 625–629.CrossRefGoogle ScholarPubMed
Yu-Hua, H., Gui-Yi, T., Yu-Qin, Q., Guo-Shen, X., Xui-Lin, W., Wui-Ming, C., De-Xin, Q., Jei-Yua, Y., Xian-Zhi, G. (1982) Comparison of pre-and post-operative radiation in the treatment of carcinoma of the maxillary sinus. International Journal of Radiation, Oncology, Biology and Physics, 8: 1045–1049.CrossRefGoogle Scholar