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Evoked response audiometry in scrub typhus: prospective, randomised, case–control study

Published online by Cambridge University Press:  04 March 2011

J S Thakur ,
N K Mohindroo ,
D R Sharma ,
K Soni  and
S S Kaushal
J S Thakur*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla, 171001, HP, India
N K Mohindroo
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla, 171001, HP, India
D R Sharma
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla, 171001, HP, India
K Soni
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla, 171001, HP, India
S S Kaushal
Affiliation:
Department of Medicine, Indira Gandhi Medical College, Shimla, 171001, HP, India
*
Address for correspondence: Dr Jagdeep S Thakur, Dept of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla, HP, 171001, India. Fax: +91 177 2800224 E-mail: anujagdeep@yahoo.co.in; j.s.thakur@hotmail.com
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Abstract

Objective:

To investigate the hypothesis of cochlear and retrocochlear damage in scrub typhus, using evoked response audiometry.

Study design:

Prospective, randomised, case–control study.

Methods:

The study included 25 patients with scrub typhus and 25 controls with other febrile illnesses not known to cause hearing loss. Controls were age- and sex-matched. All subjects underwent pure tone audiometry and evoked response audiometry before commencing treatment.

Results:

Six patients presented with hearing loss, although a total of 23 patients had evidence of symmetrical high frequency loss on pure tone audiometry. Evoked response audiometry found significant prolongation of absolute latencies of wave I, III, V, and wave I–III interpeak latency. Two cases with normal hearing had increased interpeak latencies. These findings constitute level 3b evidence.

Conclusion:

Findings were suggestive of retrocochlear pathology in two cases with normal hearing. In other patients, high frequency hearing loss may have led to altered evoked response results. Although scrub typhus appears to cause middle ear cochlear and retrocochlear damage, the presence of such damage could not be fully confirmed by evoked response audiometry.

Keywords

Audiometry, Evoked ResponseScrub TyphusRetrocochlear DiseasesHearing Loss

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 6 , June 2011 , pp. 567 - 571
Copyright
Copyright © JLO (1984) Limited 2011

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