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Do antipsychotic medications work: An exploration using competency to stand trial as the functional outcome

Published online by Cambridge University Press:  21 February 2025

Ambarin Faizi*
Affiliation:
California Department of State Hospitals
Barbara E. McDermott
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento
Katherine Warburton
Affiliation:
California Department of State Hospitals Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento
*
Corresponding author: Ambarin Faizi; Email: Ambarin.Faizi@dsh.ca.gov
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Abstract

This study explores the effectiveness of antipsychotic medications in restoring competency to stand trial in individuals with severe mental illness, particularly psychotic disorders. While antipsychotic medications are known for reducing symptoms of psychosis, this research focuses on their ability to improve functional outcomes necessary for competency to stand trial (CST). Among over 3,000 patients in California’s forensic state hospital system, 86.5% were successfully restored to competency, with 98.8% discharged on antipsychotic medications. Patients on antipsychotic monotherapy demonstrated higher restoration rates compared to those requiring additional mood stabilizers, suggesting that more complex cases demand more intensive treatment. Delusional disorder, traditionally seen as more resistant to treatment, showed a high restoration rate of 93.8% with antipsychotic use.

Our findings emphasize the pivotal role of antipsychotics in not only reducing symptoms but also in restoring critical functional abilities for participation in legal proceedings. The functional improvements they enable extend beyond the courtroom. Incorporation of antipsychotic medication as an integral evidence-based mechanism in facilitating community reintegration for individuals with severe mental illness supports the broader goal of transitioning individuals from the legal system back into society, consistent with the ultimate promise of deinstitutionalization.

Information

Type
Original Research
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press
Figure 0

Table 1. Demographic and clinical characteristics of the sample

Figure 1

Table 2. Restoration status by discharge medication

Figure 2

Table 3. Restoration to competence by discharge diagnoses

Figure 3

Table 4. Restoration to competence by discharge diagnosis—discharged only on an antipsychotic

Figure 4

Table 5. Restoration to competence by discharge diagnosis – discharged on antipsychotic and mood stabilizer

Figure 5

Table 6. Days in hospital by diagnosis—discharged restored

Figure 6

Figure 1. Days in hospital by diagnosis and medication—discharge restored.