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Leukocytes: essential cells in ovarian function and ovulation

Published online by Cambridge University Press:  03 June 2009

RJ Norman ,
N Bonello ,
MJ Jasper  and
KH Van der Hoek
RJ Norman*
Affiliation:
Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia
N Bonello
Affiliation:
Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia
MJ Jasper
Affiliation:
Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia
KH Van der Hoek
Affiliation:
Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia
*
Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital, Woodville Road, Woodville, South Australia5011.
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Extract

The disciplines of reproduction and immunology, once quite discrete, are now closely associated, with compelling evidence to suggest that immune mechanisms play important roles in the cervix, uterus, fallopian tubes and ovary. Cells and mediators classically described as part of the immune system are found throughout the reproductive tract. Disorders of reproduction, including pre-eclampsia, unexplained infertility, endometriosis, recurrent miscarriage and disturbed fetal growth almost certainly have some of their origins in the dysfunction of immune regulation. There appears to be some evidence that immune disorders, such as rheumatoid arthritis and scleroderma, can manifest as infertility, before clinical disease becomes apparent.

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Type
Research Article
Information
Reproductive Medicine Review , Volume 6 , Issue 2 , July 1997 , pp. 97 - 111
Copyright
Copyright © Cambridge University Press 1997

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