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Enhanced Osteoblast Adhesion on a Novel Hydroxyapatite Coating

Published online by Cambridge University Press:  15 February 2011

Michiko Sato
Affiliation:
School of Materials Science and Engineering
Elliott B. Slamovich
Affiliation:
School of Materials Science and Engineering
Thomas J. Webster
Affiliation:
School of Materials Science and Engineering
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Abstract

Plasma spray deposition of hydroxyapatite (HA) onto a titanium implant involves high temperatures that may alter HA crystallinity and induce cracks in the coating. For this reason, the objective of this study was to design a novel HA coating material and method. Titanium was coated with HA, titania, and Poly (dl-lactic-glycolic acid) (PLGA) using sol-gel processing. The biocompatibility of the HA coating in the present study was compared to that of a plasmasprayed HA coating. Results of this study showed that osteoblast adhesion was promoted more in the HA coating proposed in this study than on the plasma-sprayed HA coating. In addition, hydrothermal treatment of the coating appeared to improve the biocompatibility of the HA coating. Since osteoblast adhesion is a necessary requirement for increased bonding of an implant to juxtaposed bone, these results support that hydrothermally sol-gel processed HA may be an optimal implant coating material and method.

Type
Research Article
Copyright
Copyright © Materials Research Society 2003

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