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Healthcare-associated infections in Japanese hospitals: results from a large-scale multicenter point-prevalence survey in Aichi, 2020

Published online by Cambridge University Press:  08 October 2024

Hiroshi Morioka Open the ORCID record for Hiroshi Morioka [Opens in a new window] ,
Yusuke Koizumi ,
Keisuke Oka Open the ORCID record for Keisuke Oka [Opens in a new window] ,
Masami Okudaira ,
Yuka Tomita ,
Yumi Kojima Open the ORCID record for Yumi Kojima [Opens in a new window] ,
Toshitaka Watariguchi ,
Koichi Watamoto ,
Yoshikazu Mutoh  and
Takeshi Tsuji
...Show all authors
Hiroshi Morioka*
Affiliation:
Department of Infectious Diseases, Nagoya University Hospital, Nagoya, Japan
Yusuke Koizumi
Affiliation:
Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Nagakute, Japan Department of Infection Prevention and Control, Wakayama Medical University, Wakayama, Japan
Keisuke Oka
Affiliation:
Department of Infectious Diseases, Nagoya University Hospital, Nagoya, Japan Antimicrobial Stewardship Team, Kariya Toyota General Hospital, Kariya, Japan
Masami Okudaira
Affiliation:
Department of Pharmacy, Anjo Kosei Hospital, Anjo, Japan
Yuka Tomita
Affiliation:
Department of Infectious Diseases, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan
Yumi Kojima
Affiliation:
Infection Control Team, Nagoya Ekisaikai Hospital, Nagoya, Japan
Toshitaka Watariguchi
Affiliation:
Department of General Internal Medicine, Toyota Kosei Hospital, Toyota, Japan
Koichi Watamoto
Affiliation:
Department of Hematology, Komaki City Hospital, Komaki, Japan
Yoshikazu Mutoh
Affiliation:
Department of Infectious Diseases, Tosei General Hospital, Seto, Japan
Takeshi Tsuji
Affiliation:
Department of Pediatrics, Okazaki City Hospital, Okazaki, Japan
Manabu Yokota
Affiliation:
Department of Pharmacy, Handa City Hospital, Handa, Japan
Junichi Shimizu
Affiliation:
Department of Thoracic Oncology, Aichi Cancer Center Hospital, Nagoya, Japan
Chihiro Hasegawa
Affiliation:
Department of Infectious Diseases, Nagoya City University East Medical Center, Nagoya, Japan
Susumu Iwata
Affiliation:
Department of Respiratory Medicine, Kasugai Municipal Hospital, Kasugai, Japan
Masatoshi Nagaoka
Affiliation:
Department of Pharmacy, Nagoya Memorial Hospital, Nagoya, Japan
Yuji Ito
Affiliation:
Department of Respiratory Medicine, Sougo Daiyukai Hospital, Ichinomiya, Japan
Shohei Kawasaki
Affiliation:
Department of Pharmacy, Nishichita General Hospital, Tokai, Japan
Hiroki Kato
Affiliation:
Department of Infectious Diseases, Toyota Memorial Hospital, Toyota, Japan
Yuichi Kitagawa
Affiliation:
Department of Infection Control, National Center for Geriatrics and Gerontology, Obu, Japan
Takuya Goto
Affiliation:
Department of Pharmacy, NHO Nagoya Medical Center, Nagoya, Japan
Yasuhiro Nozaki
Affiliation:
Department of Respiratory Medicine, Tokoname Municipal Hospital, Tokoname, Japan
Kenji Akita
Affiliation:
Infection Control Team, Nagoya City University West Medical Center, Nagoya, Japan
Shinsuke Shimizu
Affiliation:
Infection Control Team, Kamiiida Daiichi Hospital, Nagoya, Japan
Masanori Nozawa
Affiliation:
Department of Pharmacy, Chita Kosei Hospital, Chita, Japan
Munehiro Kato
Affiliation:
Department of Respiratory Medicine, Japan Organization of Occupational Health and Safety, Asahi Rosai Hospital, Owariasahi, Japan
Masamitsu Ishihara
Affiliation:
Department of Internal Medicine, Holy Spirit Hospital, Nagoya, Japan
Kenta Ito
Affiliation:
Aichi Children’s Health and Medical Center, Obu, Japan
Tetsuya Yagi
Affiliation:
Department of Infectious Diseases, Nagoya University Hospital, Nagoya, Japan
*
Corresponding author: Hiroshi Morioka; Email: morioka-hiroshi@med.nagoya-u.ac.jp
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Abstract

Objective:

Healthcare-associated infections (HAIs) pose significant challenges to healthcare systems worldwide. Epidemiological data are essential for effective HAI control; however, comprehensive information on HAIs in Japanese hospitals is limited. This study aimed to provide an overview of HAIs in Japanese hospitals.

Methods:

A multicenter point-prevalence survey (PPS) was conducted in 27 hospitals across the Aichi Prefecture between February and July 2020. This study encompassed diverse hospital types, including community, university, and specialized hospitals. Information on the demographic data of the patients, underlying conditions, devices, HAIs, and causative organisms was collected.

Results:

A total of 10,199 patients (male: 5,460) were included in this study. The median age of the patients was 73 (interquartile range [IQR]: 56–82) years, and the median length of hospital stay was 10 (IQR: 4–22) days. HAIs were present in 6.6% of patients, with pneumonia (1.83%), urinary tract infection (1.09%), and surgical site infection (SSI) (0.87%) being the most common. The prevalence of device-associated HAIs was 0.91%. Staphylococcus aureus (17.3%), Escherichia coli (17.1%), and Klebsiella pneumoniae (7.2%) were the primary pathogens in 433 organisms; 29.6% of the Enterobacterales identified showed resistance to third-generation cephalosporins. Pneumonia was the most prevalent HAI in small-to-large hospitals (1.69%–2.34%) and SSI, in extra-large hospitals (over 800 beds, 1.37%).

Conclusions:

This study offers vital insights into the epidemiology of HAIs in hospitals in Japan. These findings underscore the need for national-level PPSs to capture broader epidemiological trends, particularly regarding healthcare challenges post-COVID-19.

Information

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 45 , Issue 11 , November 2024 , pp. 1263 - 1270
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Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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