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Sarcomas of nasal cavity and paranasal sinuses: chondrosarcoma, osteosarcoma and fibrosarcoma

Published online by Cambridge University Press:  29 June 2007

V. Koka ,
R. Vericel ,
E. Lartigau ,
A. Lusinchi  and
G. Schwaab
V. Koka
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
R. Vericel
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
E. Lartigau
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
A. Lusinchi
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
G. Schwaab*
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
*
Dr G. Schwaab, Département de Chirurgie Cervico-Faciale, Institut Gustave Roussy, Rue Camille Desmoulins, 94805 Villejuif cedex, Paris, France.
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Abstract

Forty-two patients were treated for sarcoma of the nasal cavity and paranasal sinuses at the Institut Gustave Roussy, Paris, between 1960 and 1993. Twelve patients had chondrosarcoma (CS), 14 had osteosarcoma (OS) and 16 had fibrosarcoma (FS). Ten patients had grade I, six grade II and 26 grade HI tumours.

All but 10 patients had surgery for the primary tumour. A significantly increased risk of local failure was associated with the male sex (p <0.01), grade III tumours (p <0.02) and patients excluded from surgery (p <0.04). The overall incidence of local and distant failure was 76 and 12 per cent respectively. Overall survival was 28 per cent at three years and 23 per cent at five years. Eight patients (20 per cent) were alive more than 10 years later. The factors significantly influencing survival were sex (p <0.01), grade (p <0.05) and local failure (p<0.01).

Keywords

Paranasal sinus neoplasmsNasal neoplasmsChondrosarcomaOsteosarcomaFibrosarcomaSurgeryRadiotherapyChemotherapyadjuvantCombined modality therapy

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 11 , November 1994 , pp. 947 - 953
Copyright
Copyright © JLO (1984) Limited 1994

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