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Infantile haemangiopericytoma: a rare congenital cervical tumour

Published online by Cambridge University Press:  10 February 2014

E M Farrar ,
J E H Bates ,
S Bitetti  and
I A Bruce
E M Farrar*
Affiliation:
Paediatric ENT Department, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
J E H Bates
Affiliation:
Paediatric ENT Department, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
S Bitetti
Affiliation:
Department of Paediatric Histopathology, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
I A Bruce
Affiliation:
Paediatric ENT Department, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK Respiratory and Allergy Centre, Institute of Inflammation and Repair, University of Manchester, Manchester, UK
*
Address for correspondence: Ms Eleanor M Farrar, Paediatric ENT Department, Royal Manchester Children's Hospital, Oxford Road, Manchester, M139WL E-mail: efarrar@doctors.org.uk
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Abstract

Objective:

Infantile haemangiopericytoma is a rare childhood vascular tumour of borderline malignancy and unpredictable clinical course. It can present a diagnostic challenge due to indeterminate clinical, radiological and pathological features. This report presents the case of a large congenital haemangiopericytoma of the neck in a neonate, and discusses diagnosis, imaging, pathology and surgical management.

Clinical presentation:

A full-term neonate presented with a large posterior neck mass at birth. Pre-operative radiological appearances were suggestive of teratoma, but following surgical excision the diagnosis of infantile haemangiopericytoma was confirmed on histological analysis. There were no signs of recurrence at 12-month follow up.

Conclusion:

Haemangiopericytoma can follow an aggressive course in adults, including local recurrence and metastasis. The infantile variant is rare but typically follows a distinct clinical course, and is associated with more benign behaviour compared with similar tumours in adults and children over one year. Congenital haemangiopericytoma can be effectively treated with surgery, without requiring adjuvant therapy.

Keywords

HemangiopericytomaCongenitalSurgeryNeck

Information

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 2 , February 2014 , pp. 212 - 215
Copyright
Copyright © JLO (1984) Limited 2014 

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References

1North, PE, Waner, M, Buckmiller, L, James, CA, Milm, MC. Vascular tumours of infancy and childhood: beyond capillary hemangioma. Cardiovasc Pathol 2006;15:303–17CrossRefGoogle ScholarPubMed
2Stout, A, Murray, M. Hemangiopericytoma: a vascular tumor featuring Zimmermann's pericytes. Ann Surg 1942;116:26–33Google Scholar
3Mentzel, T, Calonje, E, Nascimento, AG, Fletcher, CD. Infantile hemangiopericytoma versus infantile myofibromatosis. Study of a series suggesting a continuous spectrum of infantile myofibroblastic lesions. Am J Surg Pathol 1994;18:922–30Google Scholar
4Michael, K, Eikmeier, A, Mueller, V. Infantile hemangiopericytoma. J Diagnost Med Sonogr 2010;26:198–201Google Scholar
5Rodriguez-Galindo, C, Ramsey, K, Jenkins, JJ, Poquette, CA, Kaste, SC, Merchant, TE et al. Hemangiopericytoma in children and infants. Cancer 2000;88:198–2043.0.CO;2-W>CrossRefGoogle ScholarPubMed
6Virden, CP, Lynch, FP. Infantile hemangiopericytoma: a rare cause of a soft tissue mass. J Pediatr Surg 1993;28:741–3CrossRefGoogle ScholarPubMed
7Sepulveda, W, Muhlhausen, G, Flores, X, Gutierrez, J, Avila, R. Giant hemangiopericytoma of the fetal neck: prenatal two- and three-dimensional sonographic findings. J Ultrasound Med 2003;22:831–5Google Scholar
8Hsu, PY, Hsu, WM, Huang, HY, Chen, CY, Chou, HC, Tsao, PN et al. Congenital hemangiopericytoma in a neonate. J Formos Med Assoc 2006;105:247–51CrossRefGoogle ScholarPubMed
9Juan, C, Huang, G, Chin, S, Hsueh, C, Wu, C, Hsiao, H et al. Color and duplex Doppler sonography of hemangiopericytoma. J Clin Ultrasound 2001;29:51–53.0.CO;2-4>CrossRefGoogle ScholarPubMed
10Folpe, AL, Devaney, K, Weiss, SW. Lipomatous hemangiopericytoma: a rare variant of hemangiopericytoma that may be confused with liposarcoma. Am J Surg Pathol 1999;23:1201–7Google Scholar
11Guillou, L, Gebhard, S, Coindre, JM. Lipomatous hemangiopericytoma: a fat-containing variant of solitary fibrous tumor? Clinicopathologic, immunohistochemical, and ultrastructural analysis of a series in favor of a unifying concept. Hum Pathol 2000;31:1108–15CrossRefGoogle ScholarPubMed
12Middleton, LP, Duray, PH, Merino, MJ. The histological spectrum of hemangiopericytoma: application of immunohistochemical analysis including proliferative markers to facilitate diagnosis and predict prognosis. Hum Pathol 1998;29:636–40Google Scholar
13Billings, KR, Fu, YS, Calcaterra, TC, Sercarz, JA. Hemangiopericytoma of the head and neck. Am J Otolaryngol 2000;21:238–43Google Scholar
14Ferigo, N, Cottalorda, J, Allard, D, Gentil-Perret, A, Fessy, M, Berger, C et al. Successful treatment via chemotherapy and surgical resection of a femoral hemangiopericytoma with pulmonary metastasis. J Pediatr Hematol Oncol 2006;28:237–40CrossRefGoogle ScholarPubMed