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Acquired immunodeficiency syndrome related Kaposi's sarcoma eroding the maxillary bone

Published online by Cambridge University Press:  25 May 2007

P A Konstantinopoulos ,
H Goldsztein ,
B J Dezube  and
L Pantanowitz
P A Konstantinopoulos
Affiliation:
Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
H Goldsztein
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, University of Maryland Medical Center, Baltimore, Maryland, USA
B J Dezube*
Affiliation:
Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
L Pantanowitz
Affiliation:
Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts, USA
*
Address for correspondence: Dr Bruce J Dezube, Beth Israel Deaconess Medical Center, 330 Brookline Ave, CC-913, Boston, MA 02215, USA. Fax: +1 (617) 975 8030 E-mail: bdezube@bidmc.harvard.edu
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Abstract

Background:

Oral involvement is a common manifestation of acquired immunodeficiency syndrome related Kaposi's sarcoma, and it occurs in approximately one-third of afflicted patients.

Methods:

We report an unusual case of Kaposi's sarcoma of the hard palate which invaded the underlying maxillary bone.

Results:

The patient underwent excisional biopsy and was subsequently treated with localised radiation and systemic chemotherapy including liposomal doxorubicin.

Conclusions:

The presentation, differential diagnosis, radiographic appearance and management of this serious complication are discussed. Our case highlights the need for a multidisciplinary approach, consisting of ENT, oncology and infectious disease consultation, to ensure appropriate management of maxillofacial, intraosseous, acquired immunodeficiency syndrome related Kaposi's sarcoma.

Keywords

AIDSKaposi's SarcomaMaxillary Bone
Type
Clinical Record
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 9 , September 2008 , pp. 993 - 997
Copyright
Copyright © JLO (1984) Limited 2007

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