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The association between the reflux symptoms index and nasal symptoms among patients with non-allergic rhinitis

Published online by Cambridge University Press:  26 January 2021

A W Hamizan ,
Y Y Choo ,
P V Loh ,
N F Abd Talib ,
M F Mohd Ramli ,
F D Zahedi  and
S Husain
A W Hamizan*
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Y Y Choo
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
P V Loh
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
N F Abd Talib
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
M F Mohd Ramli
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
F D Zahedi
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
S Husain
Affiliation:
Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
*
Author for correspondence: Dr Aneeza W Hamizan, 9th Floor, Department of Otorhinolaryngology, UKM Medical Center, Jalan Yaacob Latiff, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia E-mail: draneeza@gmail.com Fax: +60 3 9145 6675
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Abstract

Background

Laryngopharyngeal reflux symptoms assessed with the reflux symptom index can overlap with non-allergic rhinitis symptoms. This study aims to explore the association between the reflux symptom index and nasal symptoms in non-allergic rhinitis patients.

Methods

A cross-sectional study was conducted on consecutive adults with non-allergic rhinitis. The reflux symptom index (score of more than 13 = laryngopharyngeal reflux) and nasal symptoms (categorised as mild (total score of 0–3), moderate (4–7) or severe (8–12)) were assessed.

Results

The study included 227 participants (aged 58.64 ± 12.39 years, 59.5 per cent female). The reflux symptom index scores increased with total nasal symptom scores (mild vs moderate vs severe, 8.61 ± 6.27 vs 12.94 ± 7.4 vs 16.40 ± 8.10; p < 0.01). Logistic regression indicated that laryngopharyngeal reflux is more likely in patients with severe nose block (odds ratio 5.47 (95 per cent confidence interval = 2.16–13.87); p < 0.01).

Conclusion

Laryngopharyngeal reflux symptoms are associated with nasal symptom severity, and nasal symptoms should be primarily treated. Those with predominant nose block and laryngopharyngeal reflux symptoms are more likely to have laryngopharyngeal reflux.

Keywords

RhinitisVasomotorLaryngopharyngeal Reflux

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 135 , Issue 2 , February 2021 , pp. 142 - 146
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr A W Hamizan takes responsibility for the integrity of the content of the paper

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