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Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial

Published online by Cambridge University Press:  31 March 2025

Sherinah Saasa*
Affiliation:
School of Social Work, Brigham Young University, Provo, UT, USA
Kaitlin P. Ward
Affiliation:
Department of Psychology, School of Social Work, University of Michigan-Ann Arbor, Ann Arbor, MI, USA
Cleopas G. Sambo
Affiliation:
Department of Social Work & Sociology, University of Zambia, Lusaka, Zambia
Paula Barrett
Affiliation:
Friends Resilience Programs, Brisbane, Australia
Cheuk Yan Lau
Affiliation:
School of Arts and Humanities, Edith Cowan University, Joondalup, Australia
*
Corresponding author: Sherinah Saasa; Email: sherinah_saasa@byu.edu
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Abstract

While many children in Africa face notable psychological problems, the majority do not receive needed mental health services. The My FRIENDS Youth Program, a universal cognitive-behavioral intervention for anxiety prevention and resilience enhancement, has demonstrated effectiveness across cultures in children and adolescents. This study explores whether the program’s effectiveness extends to Zambian children. Participants were 75 children and adolescents (53% female, ages 10–15) attending low-income schools in Zambia. Four schools were randomly assigned to an intervention (n = 44) or waitlist control (n = 31). The intervention consisted of 10 weekly sessions plus two booster sessions administered in group format. Assessments were conducted at pre-intervention, immediately post-intervention and 3-month follow-up. Data were analyzed using longitudinal multilevel modeling and controlled for child and parent sociodemographic characteristics. Intervention participation did not lead to reductions in anxiety, depression or parent-child relationship conflict but was associated with reductions in parent-reported internalizing and externalizing symptoms, attention problems and increases in positive parent-child relationships. However, both the intervention and control groups exhibited lower anxiety symptoms from Post-Intervention to 3-Month Follow-Up, suggesting potentially delayed effects. Future research may need to adapt this intervention to meet the needs of children in Zambia.

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Research Article
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press
Figure 0

Figure 1. Consort flow diagram.

Figure 1

Table 1. Baseline differences in study variables by group assignment (N = 75)

Figure 2

Table 2. Means and standard deviations of outcome variables over time (N = 75)

Figure 3

Table 3. Results from multilevel models testing interactions between wave and intervention assignment

Figure 4

Table 4. Results from multilevel models testing changes in outcomes across time for intervention and waitlist control groups

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Author comment: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R0/PR1

Comments

August 21, 2024

Editors-in-Chief

Global Mental Health

Dear Editor[s],

On behalf of my co-authors and I, please see attached a copy of the manuscript titled, “Efficacy of a School-Based Mental Health Intervention Among Zambian Youth: A Randomized Controlled Trial,” submitted for publication consideration to Global Mental Health.

The authors evaluated the effectiveness of the My FRIENDS Youth program, a universal cognitive behavioral intervention for anxiety prevention and resilience enhancement, among Zambian children and adolescents (n = 75). We enlisted a treatment and waitlist control group derived from 5th grade students from marginalized backgrounds with data collected at pre, post and 3-month follow up. Findings suggest potentially delayed effects of the intervention on reducing anxiety and depression symptoms. Further, intervention participation showed reductions in parent-reported emotional and behavioral problems, and improvements in parent-child relationship quality.

Despite increased vulnerability for mental health distress among sub-Saharan African children, this is a grossly understudied area across disciplines with very few advocates. Given the limited mental health support services for children in Africa, it is our hope that our study can shed some light on effective mental health intervention programs for this population, inform public health intervention and invite further inquiry in finding solutions for better quality of life for vulnerable children.

While portions of this manuscript were presented at the 2024 Global Social Work and Social Development conference in Panama, this manuscript has not been published elsewhere, nor is it under publication review. Finally, this manuscript was produced consistent with the ethical standards for protecting human research participants through Brigham Young University’s internal review board, the University of Zambia ethical review board and permission from the Zambian Ministry of Education. All authors have reviewed the manuscript, report no conflicts of interest and approve the manuscript for submission. We look forward to an early and positive decision concerning this submission. Thank you for your consideration.

Sincerely,

Sherinah Saasa, Ph.D., LCSW

Associate Professor

BYU School of Social Work

2173 JFSB, Provo UT 84602

Phone: 801-422-4687; Email: sherinah_saasa@byu.edu

Review: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R0/PR2

Conflict of interest statement

Reviewer declares none.

Comments

This paper reports what is effectively a cluster randomised controlled trial rather than a basic RCT, as the unit of randomisation is the school. There is no power calculation presented in the methods to predetermine number of clusters and cluster size. There is no differentiation of primary and secondary outcomes. There are only four schools in total, ie two schools in each arm of the study, which I suspect is too small a number of clusters and should probably be at least four schools per arm and possibly more. I do not know if the number of children recruited in each cluster is adequate for only two schools in each cluster or indeed if there had been at least four schools in each cluster. The flow diagram does not address how many children were in each fifth year class. It seems that children and parents were asked to express interest in the study ie to volunteer rather than being systematically approached and asked for consent. We do not know what proportion of children in each class expressed interest in the study, prior to being assessed for eligibility for inclusion. It therefore appears that the method of recruitment of children into each cluster was not systematic but rather a volunteer sample which would have led to selection biases. The numbers in the flow diagram do not always add up, eg out of 44 children assigned to treatment, 31 received it, and 10 did not, but what happened to the other 3??

It is important to know whether the research assistants were blind to cluster allocation?

The title of the paper needs to identify that this is a cluster RCT, and to indicate if it was blinded or double blinded or neither.

The limitations section of the paper does not address these issues.

I think the paper could conceivably be reported as a pilot study to assess feasibility of such a study in Zambian schools, to tighten the methodological procedures and to explore the need for more adaptation of the treatment method.

Review: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R0/PR3

Conflict of interest statement

Reviewer declares none.

Comments

I have read with interest the paper.

It adds to the literature regarding research to improve mental health of school-going children in low-income countries. However, I have a few revisions to suggest.

1.The FRIENDS program is essentially a prevention program, as such the authors would do well by emphasizing this from the outset and throughout the manuscript. There is some confusion regarding the use of the term intervention versus treatment, I would suggest they avoid the term treatment, despite the trial suggesting treatment effects were measured. This way, the lack of significant improvement or unexpected results across both case and control groups would be understandable.

2.Please consider indicating you obtained assent and not consent from the child participants.

3.Consider discussing results in context and compare with trials in low-income countries if any, in part because the challenges of doing research in a relatively unstructured school environment might be unique.

4.It is unclear why the interviews, despite the challenges of comprehending the questionnaires, were self-adminstered by the students,and not interviewer-administered. Could this have affected completion rates towards the end of the study?

5.Please describe more clearly the Time points for the control group, Do they complete questionnaires at additional time points after the intervention groups have concluded? explain the extra time point for the control group.

6.To what extent were the class teachers involved and were specific times allocated during the two meetings per week over 6 weeks? Were the groups meetings at the beginning, middle or towards the end of the school term?

7.The results based on the GAD and PHQ-9 scores across the two groups are not reflected. It is possible that the lack of improvement or change in anxiety or depression symptoms might be due to the fact that across both groups, levels of anxiety and depression were not clinically significant in the first place.

8.It is unclear if there were any untoward effects of the study among participants, given the potential distress among those included in the study based on having higher scores on GAD and PHQ-9. Did any of the participants need counseling or otherwise?

Thank you.

Recommendation: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R0/PR4

Comments

Dear Authors,

Your manuscript: “Efficacy of a School-Based Mental Health Intervention Among Zambian Youth: A Randomized Controlled Trial”, has now been reviewed,

Decision: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R0/PR5

Comments

No accompanying comment.

Author comment: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R1/PR6

Comments

February 10, 2025

Editors-in-Chief

Global Mental Health

Dear Editor[s],

On behalf of my co-authors and I, please see attached a revised copy of the manuscript titled “Efficacy of a School-Based Mental Health Intervention Among Zambian Youth: A Cluster-Randomized Controlled Trial,” resubmitted for publication consideration to Global Mental Health.

The authors are grateful for the thorough feedback from reviewers and are thankful for the opportunity to revise and resubmit our manuscript. We have reviewed each reviewer’s comments and made the needed revisions to the manuscript. Additionally, a response memo has been provided to indicate how the authors have addressed each reviewer’s recommendations. In addition, a public statement for the educated public is also available in the manuscript document per resubmission instructions.

While portions of this manuscript were presented at the 2024 Global Social Work and Social Development conference in Panama, this manuscript has not been published elsewhere, nor is it under publication review. Finally, this manuscript was produced consistent with the ethical standards for protecting human research participants through Brigham Young University’s internal review board, the University of Zambia ethical review board and permission from the Zambian Ministry of Education. All authors have reviewed the manuscript, report no conflicts of interest and approve the manuscript for submission. We look forward to an early and positive decision concerning this submission. Thank you for your consideration.

Sincerely,

Sherinah Saasa, Ph.D., LCSW

Associate Professor

BYU School of Social Work

2173 JFSB, Provo UT 84602

Phone: 801-422-4687; Email: sherinah_saasa@byu.edu

Recommendation: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R1/PR7

Comments

Dear Ms Saasa,

Your revised manuscript titled “Efficacy of a School-Based Mental Health Intervention Among Zambian Youth: A Cluster-Randomized Controlled Trial” has now been reviewed

A minor comment on page 5, line 3 reading..’Thus, the importance of prevention, early diagnosis and treatment cannot be overstated..‘ In public health, it is understood that early diagnosis and treatment are components of prevention(Secondary prevention). I suggest that the word ’primary' be inserted before prevention.

Decision: Efficacy of a school-based mental health intervention among Zambian youth: a cluster-randomized controlled trial — R1/PR8

Comments

No accompanying comment.