Hostname: page-component-75d7c8f48-fdrlk Total loading time: 0 Render date: 2026-03-14T06:20:32.139Z Has data issue: false hasContentIssue false
  • English
  • Français

The impact of environmental cleaning protocol featuring PX-UV in reducing the incidence of multidrug-resistant gram-negative healthcare-associated infection and colonization in intensive care units in Thailand

Published online by Cambridge University Press:  13 December 2023

Supavit Vaivoothpinyo ,
Ornnicha Sathitakorn ,
Kittiya Jantarathaneewat Open the ORCID record for Kittiya Jantarathaneewat [Opens in a new window] ,
David J. Weber Open the ORCID record for David J. Weber [Opens in a new window] ,
Piyaporn Apisarnthanarak ,
Sasinuch Rutjanawech ,
Pichaya Tantiyavarong Open the ORCID record for Pichaya Tantiyavarong [Opens in a new window]  and
Anucha Apisarnthanarak
Supavit Vaivoothpinyo
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
Ornnicha Sathitakorn
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
Kittiya Jantarathaneewat
Affiliation:
Department of Pharmaceutical Care, Faculty of Pharmacy, Thammasat University, Pathum Thani, Thailand Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
David J. Weber
Affiliation:
University of North Carolina, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States
Piyaporn Apisarnthanarak
Affiliation:
Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Sasinuch Rutjanawech
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
Pichaya Tantiyavarong
Affiliation:
Department of Clinical Epidemiology, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
*
Corresponding author: Anucha Apisarnthanarak; Email: anapisarn@yahoo.com
Get access Rights & Permissions [Opens in a new window]

Abstract

In this quasi-experimental study, implementing PX-UV to the standard environmental cleaning protocol was associated with a reduction in the overall incidence of multidrug-resistant (MDR) gram-negative organisms (P = .01) and MDR Acinetobacter baumannii (P = .001) in intervention intensive care units. However, the intervention did not reduce patient length of stay and 30-day mortality.

Information

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 45 , Issue 5 , May 2024 , pp. 684 - 687
Check for updates
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Siwakoti, S, Subedi, A, Sharma, A, Baral, R, Bhattarai, NR, Khanal, B. Incidence and outcomes of multidrug-resistant gram-negative bacteria infections in intensive care unit from Nepal—a prospective cohort study. Antimicrob Resist Infect Control 2018;7:114.10.1186/s13756-018-0404-3CrossRefGoogle ScholarPubMed
Weber, DJ, Anderson, D, Rutala, WA. The role of the surface environment in healthcare-associated infections. Curr Opin Infect Dis 2013;26:338–344.10.1097/QCO.0b013e3283630f04CrossRefGoogle ScholarPubMed
Kanamori, H, Rutala, WA, Gergen, MF, et al. Microbial assessment of healthcare-associated pathogens on various environmental sites in patient rooms after terminal room disinfection. Open Forum Infect Dis 2021;8:ofab008.10.1093/ofid/ofab008CrossRefGoogle Scholar
Sathitakorn, O, Jantarathaneewat, K, Weber, DJ, Apisarnthanarak, P, Rutjanawech, S, Apisarnthanarak, A. Efficacy of environmental cleaning protocol featuring real-time feedback with and without PX-UV in reducing the contamination of gram-negative microorganisms on high-touch surfaces in four intensive care units in Thailand. Antibiotics (Basel) 2023;12:438.CrossRefGoogle ScholarPubMed
Nerandzic, MM, Cadnum, JL, Pultz, MJ, Donskey, CJ. Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. BMC Infect Dis 2010;10:197.10.1186/1471-2334-10-197CrossRefGoogle ScholarPubMed
Anderson, DJ, Chen, LF, Weber, DJ, et al. Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study. Lancet 2017;389:805–814.CrossRefGoogle ScholarPubMed
Dancer, SJ, King, MF. Systematic review on use, cost, and clinical efficacy of automated decontamination devices. Antimicrob Resist Infect Control 2021;10:34.10.1186/s13756-021-00894-yCrossRefGoogle ScholarPubMed
Yungyuen, T, Chatsuwan, T, Plongla, R, et al. Nationwide surveillance and molecular characterization of critically drug-resistant gram-negative bacteria: results of the Research University Network Thailand Study. Antimicrob Agents Chemother 2021;65:e0067521.10.1128/AAC.00675-21CrossRefGoogle ScholarPubMed
Ling, ML, Apisarnthanarak, A, Thu le, TA, Villanueva, V, Pandjaitan, C, Yusof, MY. APSIC guidelines for environmental cleaning and decontamination. Antimicrob Resist Infect Control 2015;4:58.CrossRefGoogle Scholar
Kumar, VA, Khan, S. Defining multidrug resistance in gram-negative bacilli. Indian J Med Res 2015;141:491.CrossRefGoogle ScholarPubMed
National Healthcare Safety Network (NHSN) patient safety component manual 2022. US Centers for Disease Control and Prevention website. https://www.cdc.gov/nhsn/pdfs/validation/2022/pcsmanual_2022_508.pdf. Accessed February 1, 2022.Google Scholar
Hosein, I, Madeloso, R, Nagaratnam, W, Villamaria, F, Stock, E, Jinadatha, C. Evaluation of a pulsed xenon ultraviolet light device for isolation room disinfection in a United Kingdom hospital. Am J Infect Control 2016;44:e157–e161.10.1016/j.ajic.2016.01.044CrossRefGoogle Scholar
Morikane, K, Suzuki, S, Yoshioka, J, Yakuwa, J, Nakane, M, Nemoto, K. Clinical and microbiological effect of pulsed xenon ultraviolet disinfection to reduce multidrug-resistant organisms in the intensive care unit in a Japanese hospital: a before–after study. BMC Infect Dis 2020;20:82.10.1186/s12879-020-4805-6CrossRefGoogle Scholar
Supplementary material: File

Vaivoothpinyo et al. supplementary material

Tables S1-S3

Download Vaivoothpinyo et al. supplementary material(File)
File 28.2 KB