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Peak nasal inspiratory flow – the plateau effect

Published online by Cambridge University Press:  29 June 2007

R. W. Clarke ,
A. S. Jones  and
H. Richardson
R. W. Clarke*
Affiliation:
Department of Otorhinolaryngology, University of Liverpool, Liverpool.
A. S. Jones
Affiliation:
Department of Otorhinolaryngology, University of Liverpool, Liverpool.
H. Richardson
Affiliation:
Department of Otorhinolaryngology, University of Liverpool, Liverpool.
*
Mr R. W. Clarke, Senior Registrar, Department of Otorhinolaryngology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JE.
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Abstract

To study the efficacy of peak nasal inspiration flow (PNIF) as a means of recording change in nasal patency 20 subjects were given increasing doses of intranasal 5tometazo1ine. Nasal resistance (NR) and peak nasal inspiratory flow (PNIF) were measured in the resting stateand after each xylometazoline administration. Successive increases in dose caused a progressive decrease in nasal resistance and an increase in PNIF but the change in peak nasal inspiratory flow (PNIF) was much less. Peak nasal inspiratory flow shows a plateau effect as nasal resistance decreases. The reasons for this plateau are discussed in terms of respiratory flow mechanics

Keywords

NoseAirway resistanceFlow meters

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 5 , May 1995 , pp. 399 - 402
Copyright
Copyright © JLO (1984) Limited 1995

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References

Aschen, G., Drettner, B., Ronge, A. E. (1958) A new technique for measuring nasal airflow resistance to breathing illustrated by the effect of histamine and physical effort. Annales Academiae Regiae Scientiarum Upsaliensis 2: 111–126.Google Scholar
Benson, M. K. (1971) Maximum nasal inspiratory flow rate. Its use in assessing the effect of pseudoephedrine in vasomotor rhinitis European Journal of Clinical Pharmacology 3: 182–184.Google Scholar
Clarke, R. W., Jones, A. S. (1994) The limitations of peak nasal flow measurement. Clinical Otolaryngology 19: 502–504.CrossRefGoogle ScholarPubMed
Clement, P. A. (1984) Committee report on the standardization of rhinomanometry. Rhinology 22: 151–155.Google ScholarPubMed
Corrado, O. J., Gould, C. A., Kassab, J. Y., Davies, R. J. (1986) Nasal response of rhinitic and non-rhinitic subjects to histamine and methacholine: a comparative study. Thorax 41: 863–868.CrossRefGoogle ScholarPubMed
Hoffman, B. B., Lefkowitz, R. J. (1990) Catecholamines and sympathomimetric drugs. In Goodman and Gilman's The Pharmacological Basis of Therapeutics. (Gilman, A. G., Rail, T. W., Nies, A. S.Taylor, P., eds.), 8th Edition, Pergamon Press London, pp 216.Google Scholar
Jones, A. S., Lancer, J. M., Stevens, J. A., Beckingham, E. (1987) Nasal resistance to airflow: its measurement, reproducibility and normal parameters Journal of Laryngology and Otology 101: 800–808.CrossRefGoogle ScholarPubMed
Jones, A. S., Viani, L., Phillips, D. E., Charters, P. (1991) The objective assessment of nasal patency. Clinical Otolaryngology 16: 206–211.CrossRefGoogle ScholarPubMed
Röhrer, E. (1915) Der stromungwiderstand in den menschlichen atemwegen und der einfluss der unregelmassigen ver zweigen der bronchial systems auf den atmungsverflauf verschiedenen lungenbezirken. Pfugers Archives Ges Physiologie 162: 225–296.CrossRefGoogle Scholar
Stocksted, P. (1953) Measurement of resistance in the nose during respiration at rest. Acta Otolaryngologica (Stockholm) 109 (suppl.): 159–175.Google Scholar
Uddstromer, M. (1940) Nasal respiration. Acta Otolaryngologica (Stockholm) 42 (suppl.): 15.Google Scholar
Wright, B. M., McKerrow, C. B., (1959) Maximum forced expiration flow rate as a measure of ventilation capacity. British Medical Journal 9: 1041–1047.CrossRefGoogle Scholar
Youlten, L. J. F. (1980) The peak nasal inspiratory flow meter: a new instrument for assessment of the response to immunotherapy in seasonal allergic rhinitis. Allergologia et Immunopathologia 8: 344–347.Google Scholar
Zwaardemaker, H. (1889) Ademanslaag a Diagnosticum nasal stenose. Nederlands Tijdschrift voor Geneeskunde 25: 297–300.Google Scholar