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The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts

Published online by Cambridge University Press:  04 September 2025

Shankar Chakkera
Affiliation:
Johns Hopkins University , Baltimore, MD, USA
Julia Sieg
Affiliation:
Faculty of Behavioural and Cultural Studies, Heidelberg University , Heidelberg, Germany
Theodora Khofi
Affiliation:
Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
Rosemina Ayieko
Affiliation:
Duke Global Health Institute, Duke University, Durham, NC, USA
Brandon A. Knettel*
Affiliation:
Duke Global Health Institute, Duke University, Durham, NC, USA Duke University School of Nursing, Durham, NC, USA Duke Center for Global Mental Health, Durham, NC, USA
*
Corresponding author: Brandon A. Knettel; Email: Brandon.Knettel@duke.edu
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Abstract

More than 116 million people in Africa live with mental health conditions. However, many African countries lack the infrastructure, training and workforce to effectively manage psychiatric emergencies. This has led to overuse of controversial practices such as physical and chemical restraint and involuntary seclusion, often violating patient rights. We conducted a scoping review of restraint and seclusion practices and their impacts in African clinical settings using the PubMed, Embase, CINAHL, PsycInfo and ProQuest databases. Titles/abstracts and full texts were reviewed for inclusion using the Covidence platform, and 29 studies were included in the final extraction. Restraint and/or seclusion were employed to manage aggression, enable involuntary treatment or prevent self-harm. Patients found restraint and seclusion to be dehumanizing, a cause of posttraumatic stress and a barrier to future help-seeking. Healthcare workers described inadequate training, overuse of restraint and seclusion, injuries and emotional distress after employing these treatments. Further research, intervention development and policy reform are urgently needed to promote humane and patient-centered psychiatric care, including verbal de-escalation training, in underresourced healthcare systems.

Information

Type
Review
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press
Figure 0

Figure 1. Review flowchart.

Figure 1

Table 1. Overview of included studies

Figure 2

Table 2. Key findings of the included studies

Figure 3

Figure 2. Summary of key themes reflected in the included studies.

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Author comment: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R0/PR1

Comments

Professor Judy Bass and Professor Dixon Chibanda, Editors-in-Chief

Cambridge Prisms: Global Mental Health

April 17, 2025

Dear Professors Bass and Chibanda,

Please see our enclosed manuscript, “The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts,” which we are submitting for your consideration. Many African settings are woefully under-resourced to provide mental health treatment, and in the context of inpatient management of psychiatric emergencies, this leads to inhumane and dangerous conditions for both patients and staff.

My co-authors and I have witnessed firsthand these conditions. This manuscript systematizes those experiences by rigorously reporting the findings from the current literature on the management of psychiatric emergencies in clinical settings in Africa. Importantly, we go beyond summarization to describe the implications of this literature for future clinical practice, research, and policy.

We identified 29 studies for inclusion in this review, which provide a strong window into the current conditions of psychiatric treatment in diverse African settings. Restraint and/or seclusion were employed to manage aggression, enable involuntary treatment, or prevent self-harm. Patients found restraint and seclusion to be dehumanizing, a cause of posttraumatic stress symptoms, and a barrier to future help-seeking. Healthcare workers described inadequate training, overuse of restraint and seclusion, injuries, and emotional distress after employing these treatments.

Given the broad implications and potential for high impact of this work, we believe that this manuscript is a strong fit for your journal and will be of interest to your readers. We present a sound methodological approach and analysis, and we believe this manuscript will add to the literature informing intervention development in a vital, life-saving aspect of the mental health field.

The manuscript has not been previously published, nor has it been submitted for publication elsewhere. We declare that we have no conflicts of interest in relation to this research and all sources of support have been appropriately disclosed. The authors are the sole owners of the compiled data, which may be made available upon request. All listed authors contributed substantially to the work and manuscript according to ICMJE criteria.

Thank you for your consideration. We look forward to your review and to the possibility of having our work published in Cambridge Prisms: Global Mental Health.

Sincerely,

Brandon A. Knettel, Ph.D.

Associate Director, Duke Center for Global Mental Health

Duke University School of Nursing and Duke Global Health Institute

Review: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R0/PR2

Conflict of interest statement

Reviewer declares none.

Comments

This is a well-structured and timely scoping review that addresses a critical gap in the literature on psychiatric emergency management in African clinical settings. The topic is of high relevance, however, the manuscript can benefit from clearer methodological justification, deeper synthesis of findings, and expanded discussion on global and regional policy implications.

Comments to the authors

1. Include terminology consistency and definitions early

In Lines: 68–75, the definition of restraint and seclusion appears mid-way through the background; they should be defined upfront.

2. Expand the global context

In Lines: 86–96, “In high-income global settings, efforts have included mandated training… It will be crucial to implement similar strategies in other global settings, including throughout the continent of Africa.” This paragraph is too brief and under-referenced. The authors can expand by comparing Africa’s situation with countries implementing specific reforms.

3. Strengthen the rationale for a Scoping Review

In the Lines: 97–101 “The objective of this manuscript is to conduct a scoping review of studies describing the use of restraint and seclusion…” The rationale for using a scoping review method is not well-articulated. The authors can add a brief explanation to strengthen the rationale.

4. Data extraction approach needs more depth

In Lines: 159–161, “Studies deemed eligible… were assigned for data extraction by one team member, with review and quality check by a second team member…” This is descriptive but lacks analytic insight. The authors can add details on how the extracted data were organized.

5. Clarify the Scope of ‘Africa’

Under the results (Lines: 163–181) “Of the 29 included studies, seven studies were conducted in South Africa... one in Morocco.” The findings may be biased due to more concentration of studies in only a few African countries. The authors can add a clarifying statement in the Introduction or Methods acknowledging that regional representation is uneven and discuss how this may limit the generalizability of the review findings across Africa.

6. Balance between quantitative and qualitative data

Lines: 174–181, Although the studies consisted of 14 quantitative and 11 qualitative, the quantitative findings are under-discussed compared to qualitative narratives. The authors can expand the Results section with comparative metrics.

7. Policy recommendations should be actionable

In Lines: 319–321, “Many studies pointed to policy implications… must be complemented by systemic and behavioral changes…” Policy recommendations are too broad, specify using some examples. On note line 323, “Expand on this.” Did the authors intend to expand on this?

8. Limitations section needs expansion

Under discussion, “Furthermore, the absence of culturally informed interventions and comprehensive documentation limits the ability to implement effective reforms.” This is phrased as a discussion point rather than a structured limitations section. The authors can add it to the limitations paragraph.

9. The limitations of the scoping review (e.g., language restriction to English, exclusion of grey literature in some regions, limited generalizability due to geographic skew) should be explicitly listed and discussed.

Review: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R0/PR3

Conflict of interest statement

Reviewer declares none.

Comments

• This is a well-written and timely paper addressing a highly relevant topic in African mental health care.

• The authors are encouraged to clarify their database selection. Specifically, why was African Journals Online (AJOL) not included in the search strategy, given its relevance to regional research?

• There is some inconsistency in the referencing format. At times, only surnames are used, while in other instances, both surnames and initials appear. Please ensure uniformity throughout the manuscript.

• The statement: “We also examine strategies that have been implemented to reduce restraint and seclusion, which may inform future efforts to improve patient safety and uphold ethical standards in mental health care” may be misleading. The review did not include studies explicitly focused on implementation of strategies, and this should be accurately reflected in the discussion.

• While the paper rightly identifies the need for context-appropriate solutions, it is important to acknowledge that effective strategies already exist. Rather than reinventing the wheel, the focus should be on adapting and implementing existing models within African contexts.

Recommendation: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R0/PR4

Comments

Thank you for the submission of your manuscript to Cambridge Prisms: Global Mental Health. As both reviewers indicate, your manuscript makes and important contribution to the field of Global Mental Health. Both reviewers do, however make recommendations for strengthening of the manuscript. Kindly attend to these comments and make a re-submission.

Decision: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R0/PR5

Comments

No accompanying comment.

Author comment: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R1/PR6

Comments

Brandon A. Knettel, Ph.D.

Email: Brandon.Knettel@duke.edu

Professor Judy Bass and Professor Dixon Chibanda, Editors-in-Chief

Cambridge Prisms: Global Mental Health

July 10, 2025

Dear Professors Bass and Chibanda,

My co-authors and I appreciate your review of our manuscript, “The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts,” and the invitation for us to revise and resubmit this work. Below you will find our responses to the reviewer comments with page numbers referring to the revised manuscript. Revisions in the manuscript were made using Track Changes.

We sincerely appreciate the thoughtfulness of the reviewers and your recognition of the importance of this topic. The suggestions have guided our conceptualization and presentation of our findings and have greatly enhanced the quality and clarity of the manuscript.

Thank you for your consideration. We look forward to your review and to the possibility of having our work published in Cambridge Prisms: Global Mental Health.

Sincerely,

Brandon A. Knettel, Ph.D.

Associate Professor and Associate Director, Duke Center for Global Mental Health

Duke University School of Nursing and Duke Global Health Institute

Review: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R1/PR7

Conflict of interest statement

Reviewer declares none.

Comments

Well done

Review: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R1/PR8

Conflict of interest statement

No conflict of interest

Comments

Thank you for your comprehensive responses and review.

The revised manuscript shows clear improvements in context, methodology, and policy relevance. All my previously noted issues, including the rationale for the scoping review, terminology consistency, and limitations, have been adequately addressed. However, a few minor stylistic and grammatical issues remain that do not hinder understanding. They are more of editorials, which can be dealt with in final proofreading.

Recommendation: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R1/PR9

Comments

No accompanying comment.

Decision: The management of psychiatric emergencies in Africa: A scoping review of restraint and seclusion practices in clinical settings and their impacts — R1/PR10

Comments

No accompanying comment.