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Closure of the nasal cavities in the treatment of refractory hereditary haemorrhagic telangiectasia

Published online by Cambridge University Press:  29 June 2007

Valerie J. Lund  and
David J. Howard
Valerie J. Lund*
Affiliation:
Institute of Laryngology and Otology, 330 Grays Inn Rd, London, UK.
David J. Howard
Affiliation:
Institute of Laryngology and Otology, 330 Grays Inn Rd, London, UK.
*
Address for correspondence: Professor V.J. Lund, M.S., F.R.C.S., Professorial Unit, Royal National Throat Nose and Ear Hospital, 330/332 Gray's Inn Road, London WC1X 8DA.
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Abstract

From a cohort of 35 patients with hereditary haemorrhagic telangiectasia (HHT), 12 patients have undergone closure of the one or both nasal cavities during the last three years for refractory epistaxis. All had failed other forms of treatment including hormone therapy, laser coagulation and septodermoplasty. All patients were available for follow-up at six months or longer. In all patients where complete closure was achieved (11 out of 12) bleeding ceased completely from the operated side.

Keywords

Hereditary haemorrhagic telangiectasiasurgery

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 1 , January 1997 , pp. 30 - 33
Copyright
Copyright © JLO (1984) Limited 1997

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References

Babington, B. G. (1865) Hereditary epistaxis. Letter to the Editor of the Lancet 2: 362–363.Google Scholar
Brooker, D. S., Cinnamond, M. J. (1991) Young's procedure in the treatment of epistaxis. Journal of Laryngology and Otology 105: 847–848.CrossRefGoogle ScholarPubMed
Gluckman, J. L., Portugal, L. G. (1994) Modified Young's procedure for refractory epistaxis due to hereditary hemorrhagic telangiectasia. Laryngoscope 104: 1174–1177.CrossRefGoogle ScholarPubMed
Harrison, D. F. N. (1956) Babington's disease, Hereditary haemorrhagic telangiectasia. Guy's Hospital Reports 104: 246–266.Google Scholar
Harrison, D. F. N. (1963) Familial haemorrhagic telangiectases. Twenty cases treated with systemic oestrogen. Quarterly Journal of Medicine 33: 25–38.Google Scholar
Harrison, D. F. N. (1982) Use of oestrogen in the treatment of familial haemorrhagic telangiectasia. Laryngoscope 92: 314–320.CrossRefGoogle Scholar
Hosni, A. A., Innes, A. J. (1994) Hereditary haemorrhagic telangiectasia: Young's procedure in the management of epistaxis. Journal of Laryngology and Otology 108: 754–757.CrossRefGoogle ScholarPubMed
Illum, P., Bjerring, P. (1988) Hereditary hemorrhagic telangiectasia treated by laser surgery. Rhinology 26(1): 19–24.Google ScholarPubMed
Jahnke, V. (1970) Ultrastructure of hereditary telangiectasia. Archives of Otolaryngology 92: 262–265.CrossRefGoogle Scholar
Koch, H. J., Escher, G. C., Lewis, J. S. (1952) Hormonal management of hereditary hemorrhagic telangiectasia. Journal of the American Medical Association 149: 1376–1380.CrossRefGoogle Scholar
Laurian, N., Kalmanovitch, M., Shimberg, R. (1979) Amniotic graft in the management of severe epistaxis due to hereditary haemorrhagic telangiectases. Journal of Laryngology and Otology 93: 589–595.CrossRefGoogle Scholar
McCabe, W. P., Kelly, A. P. (1972) Management of epistaxis i n Osler-Rendu-Weber disease. Recurrence of telangiectases within a nasal skin graft. Plastic and Reconstructive Surgery 50: 114–118.CrossRefGoogle Scholar
Menefee, M. G., Flessa, H. C., Glueck, H. I. (1957) Hereditary hemorrhagic telangiectasia. An electron microscopic study of the vascular lesions before and afer therapy with hormones. Archives of Otolaryngology 101: 246–251.CrossRefGoogle Scholar
Milton, C. M., Shotton, J. C., Premachandran, D. J., Woodward, B. M., Fabre, J. W., Sergeant, R. J. (1993) A new technique using cultured epithelial sheets for the management of epistaxis associated with hereditary haemorrhagic telangiectasia. Journal of Laryngology and Otology 107: 510–513.CrossRefGoogle ScholarPubMed
Osier, W. (1901) On a family form of recurring epistaxis associated with multiple telangiectases of skin and mucous membrane. John's Hospital Medical Bulletin 12: 333–337.Google Scholar
Richtsmeier, W., Weaver, G., Steck, W., Jacobson, H., Dewell, R., Olson, J. (1984) Estrogen and progesterone receptors in hereditary haemorrhagic telangiectasia. Otolaryngology – Head and Neck Surgery 92: 564–570.CrossRefGoogle Scholar
Saunders, W. H. (1960) Septal dermoplasty for control of nose bleeds in hereditary hemorrhagic telangiectasia. Transactions of the American Academy of Ophthalmology and Otolaryngology 64: 500–506.Google ScholarPubMed
Shapshay, S. M., Oliver, P. (1984) Treatment of hereditary hemorrhagic telangiectasia by Nd-YAG laser photocoagulation. Laryngoscope 94: 1554–1556.CrossRefGoogle ScholarPubMed
Siegel, M. B., Keane, W. M., Atkins, J. F., Rosen, M. R. (1991) Control of epistaxis in patients with hereditary hemorrhagic telangiectasia. Otolaryngology – Head and Neck Surgery 105(5): 675–679.CrossRefGoogle ScholarPubMed
Sutton, H. G. (1864) Epistaxis as an indicator of impaired nutrition and degeneration of the vascular system. Medical Mirror 1: 769–771.Google Scholar
Taylor, M., Young, A. (1961) Histopathological and histochemical studies on atrophic rhinitis. Journal of Laryngology and Otology 75: 574–590.CrossRefGoogle ScholarPubMed
Weber, F. M. (1907) Multiple hereditary developmental angiomata of the skin and mucous membranes with recurrent haemorrhage. Lancet 2: 160–162.Google Scholar
Young, A. (1967) Closure of the nostrils in atrophic rhinitis. Journal of Laryngology and Otology 81: 515–524.CrossRefGoogle ScholarPubMed