Hostname: page-component-6766d58669-fx4k7 Total loading time: 0 Render date: 2026-05-19T13:11:53.273Z Has data issue: false hasContentIssue false
  • English
  • Français

Serum phosphohexose isomerase levels in patients with head and neck cancer

Published online by Cambridge University Press:  29 June 2007

Harish Goel ,
G. S. Kohli  and
Harbans Lal
Harish Goel
Affiliation:
Rohtak, India
G. S. Kohli
Affiliation:
Rohtak, India
Harbans Lal*
Affiliation:
Rohtak, India
*
Dr. Harbans Lal, 12/9J. Medical College, Rohtak-124001 (India).
Get access Rights & Permissions [Opens in a new window]

Abstract

Serum phosphohexose isomerase (PHI) levels were estimated in 28 patients with head and neck cancer. The mean value was significantly higher when compared to the controls. There was no difference in mean PHI value with respect to the character of the lesion or with the histopathological type of growth. The activity was increased with the advancement of the stage of cancer.

With radiotherapy, a gradual and significant decrease in serum PHI activity was observed.

Information

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 100 , Issue 5 , May 1986 , pp. 581 - 586
Copyright
Copyright © JLO (1984) Limited 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Bhatia, P. L., Singh, M. M. and Chakravorty, M. (1979) Enzymatic study in diagnosis of head and neck cancer. Indian Journal of Otolaryngology, 31: 76–79.Google Scholar
Bodansky, O. and Schwartz, M. K. (1966) Phosphohexose isomerase: Clinical aspects. Methods in Enzvmology, IX: 568–575.CrossRefGoogle Scholar
Damle, S. R., Talvdekar, R. V. and Pause, T. B. (1971) The study of glycolytic enzymes in relation to cancer. II. Comparative study of phosphohexose isomerase, aldolase, isocitrate dehydrogenase, serum glutamate. oxaloacetate transaminase and alkaline phosphatase in liver. Indian Journal of Cancer, 8: 21–29.Google Scholar
Griffith, M. M. and Beck, J. C. (1963) The value of serum phosphohexose isomerase as an index of metastatic breast carcinoma activity. Cancer, 16: 1032–1041.3.0.CO;2-B>CrossRefGoogle ScholarPubMed
Israels, L. G. and Delory, G. E. (1956) Serum isomerase in leukaemia. British Journal of Cancer, 10: 318–320.CrossRefGoogle Scholar
Joplin, G. F. and Jagatheesan, K. A. (1962) Serum glycolytic enzymes and acid phosphatase in mammary carcinomatosis. British Medical Journal, 827–831.Google Scholar
Maity, C. R. and Burma, D. P. (1973) Metabolic changes in breast carcinoma. II. Phosphohexose isomerase and lactic dehydrogenase level in serum. Indian Journal of Cancer, 10: 356–360.Google ScholarPubMed
Rao, Y. N., Chakravorty, M. and Khanna, N. N. (1976) Serum phosphohexose isomerase in cancer. Indian Journal of Cancer, 13: 361–366.Google ScholarPubMed
Schwartz, M. A., West, M., Walsh, W. S. and Zimmerman, H. J. (1962a) Serum enzymes in disease VIII. Glycolytic and oxidative enzymes and transaminases in patients with gastrointestinal carcinoma. Cancer, 15: 346–353.3.0.CO;2-W>CrossRefGoogle Scholar
Schwartz, M. A., Walsh, W. S., West, M. and Zimmerman, H. J. (1962b) Serum enzymes in disease X. Glycolytic and oxidative enzymes and transaminases in patients with carcinoma of head, neck and esophagus. Cancer, 15: 927–930.Google Scholar
UICC (1978) Report of Committee on TNM classification. Geneva.Google Scholar
Wu, R. (1959) Leakage of enzymes from ascites tumor cells. Cancer Research, 19: 1217–1222.Google ScholarPubMed