Hostname: page-component-848d4c4894-nr4z6 Total loading time: 0 Render date: 2024-05-05T10:44:48.025Z Has data issue: false hasContentIssue false
  • English
  • Français

COVID-19 vaccine willingness amongst patients with mental illness compared with the general population

Published online by Cambridge University Press:  17 May 2021

Oskar Hougaard Jefsen Open the ORCID record for Oskar Hougaard Jefsen [Opens in a new window] ,
Pernille Kølbæk Open the ORCID record for Pernille Kølbæk [Opens in a new window] ,
Yael Gil ,
Maria Speed Open the ORCID record for Maria Speed [Opens in a new window] ,
Peter Thisted Dinesen Open the ORCID record for Peter Thisted Dinesen [Opens in a new window] ,
Kim Mannemar Sønderskov Open the ORCID record for Kim Mannemar Sønderskov [Opens in a new window]  and
Søren Dinesen Østergaard Open the ORCID record for Søren Dinesen Østergaard [Opens in a new window]
Oskar Hougaard Jefsen
Affiliation:
Department of Affective Disorders, Aarhus University Hospital – Psychiatry, Aarhus, Denmark
Pernille Kølbæk
Affiliation:
Department of Affective Disorders, Aarhus University Hospital – Psychiatry, Aarhus, Denmark
Yael Gil
Affiliation:
Department of Affective Disorders, Aarhus University Hospital – Psychiatry, Aarhus, Denmark
Maria Speed
Affiliation:
Department of Affective Disorders, Aarhus University Hospital – Psychiatry, Aarhus, Denmark
Peter Thisted Dinesen
Affiliation:
Department of Political Science, University of Copenhagen, Copenhagen, Denmark
Kim Mannemar Sønderskov
Affiliation:
Department of Political Science, Aarhus University, Aarhus, Denmark
Søren Dinesen Østergaard*
Affiliation:
Department of Affective Disorders, Aarhus University Hospital – Psychiatry, Aarhus, Denmark
*
Author for correspondence: Søren Dinesen Østergaard, Email: soeoes@rm.dk
Get access Rights & Permissions [Opens in a new window]

Abstract

Patients with mental illness are at an increased risk of COVID-19 infection, morbidity, and mortality, and prioritisation of this group for COVID-19 vaccination programmes has therefore been suggested. Vaccine uptake may, however, be compromised by vaccine hesitancy amongst patients with mental illness, posing a critical public health issue. We conducted two surveys to provide weighted estimates of vaccine willingness amongst patients with mental illness and the general population of Denmark. Vaccine willingness was high in both groups, but slightly lower amongst patients with mental illness (84.8%), compared with the general population (89.5%) (p < .001). Based on these findings, vaccine hesitancy does not appear to be a major barrier for vaccine uptake amongst patients with mental illness in Denmark, but may be so in other countries with lower general vaccine willingness. Replication of the present study in other countries is strongly warranted.

Keywords

psychiatric disordersCOVID-19COVID-19 vaccinevaccine hesitancysurvey
Type
Short Communication
Information
Acta Neuropsychiatrica , Volume 33 , Issue 5 , October 2021 , pp. 273 - 276
Check for updates
Copyright
© The Author(s), 2021. Published by Cambridge University Press in association with Scandinavian College of Neuropsychopharmacology

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

*

This is an updated version of the original article. For details please see the notice at https://doi.org/10.1017/neu.2021.43.

References

Daly, M and Robinson, E (2021) Willingness to vaccinate against COVID-19 in the US: representative longitudinal evidence from April to October 2020. American Journal of Preventive Medicine 60(6): 766–773 10.1016/j.amepre.2021.01.008CrossRefGoogle Scholar
De Hert, M, Mazereel, V, Detraux, J and Van Assche, K (2021) Prioritizing COVID-19 vaccination for people with severe mental illness. World Psychiatry 20, 54.10.1002/wps.20826CrossRefGoogle ScholarPubMed
De Picker, LJ, Dias, MC, Benros, ME, Vai, B, Branchi, I, Benedetti, F, Borsini, A, Leza, JC, Kärkkäinen, H and Männikkö, M (2021) Severe mental illness and European COVID-19 vaccination strategies. The Lancet Psychiatry 8(5), 356–359.Google Scholar
Druss, BG, Rask, K and Katon, WJ (2008) Major depression, depression treatment and quality of primary medical care. General Hospital Psychiatry 30, 20–25.CrossRefGoogle ScholarPubMed
Druss, BG, Rosenheck, RA, Desai, MM and Perlin, JB (2002) Quality of preventive medical care for patients with mental disorders. Medical Care 40, 129–136.CrossRefGoogle ScholarPubMed
Kølbæk, P, Jefsen, OH, Speed, M and Østergaard, SD (2021) Mental health of patients with mental illness during the COVID-19 pandemic lockdown: a questionnaire-based survey weighted for attrition. medRxiv.CrossRefGoogle Scholar
Lazarus, JV, Ratzan, SC, Palayew, A, Gostin, LO, Larson, HJ, Rabin, K, Kimball, S and El-Mohandes, A (2020) A global survey of potential acceptance of a COVID-19 vaccine. Nature Medicine 27(2), 225–228.10.1038/s41591-020-1124-9CrossRefGoogle ScholarPubMed
Lindholt, MF, Jørgensen, FJ, Bor, A and Petersen, MB (2020) Willingness to use an approved COVID-19 vaccine: cross-national evidence on levels and individual-level predictors. PsyArXiv.CrossRefGoogle Scholar
Lord, O, Malone, D and Mitchell, AJ (2010) Receipt of preventive medical care and medical screening for patients with mental illness: a comparative analysis. General Hospital Psychiatry 32, 519–543.CrossRefGoogle ScholarPubMed
Lorenz, RA, Norris, MM, Norton, LC and Westrick, SC (2013) Factors associated with influenza vaccination decisions among patients with mental illness. The International Journal of Psychiatry in Medicine 46, 1–13.10.2190/PM.46.1.aCrossRefGoogle ScholarPubMed
Mazereel, V, Van Assche, K, Detraux, J and De Hert, M (2021) COVID-19 vaccination for people with severe mental illness: why, what, and how? The Lancet Psychiatry 8(5), 444–450.Google Scholar
Miles, LW, Williams, N, Luthy, KE and Eden, L (2020) Adult vaccination rates in the mentally ill population: an outpatient improvement project. Journal of the American Psychiatric Nurses Association 26, 172–180.10.1177/1078390319831763CrossRefGoogle ScholarPubMed
Mitchell, AJ, Malone, D and Doebbeling, CC (2009) Quality of medical care for people with and without comorbid mental illness and substance misuse: systematic review of comparative studies. The British Journal of Psychiatry 194, 491–499.CrossRefGoogle ScholarPubMed
Moberly, T (2021) Vaccine hesitancy fell after vaccination programme started. BMJ 372, n837.CrossRefGoogle ScholarPubMed
Murphy, J, Vallières, F, Bentall, RP, Shevlin, M, Mcbride, O, Hartman, TK, Mckay, R, Bennett, K, Mason, L and Gibson-Miller, J (2021) Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom. Nature Communications 12, 1–15.CrossRefGoogle ScholarPubMed
Østergaard, SD, Schmidt, M, Horváth-Puhó, E, Thomsen, RW and Sørensen, HT (2021) Thromboembolism and the Oxford–AstraZeneca COVID-19 vaccine: side-effect or coincidence? The Lancet. 397 (10283), 1441–1443.10.1016/S0140-6736(21)00762-5CrossRefGoogle ScholarPubMed
Robertson, E, Reeve, KS, Niedzwied, z, CL, Moore, J, Blake, M, Green, M, Katikireddi, SV and Benzeval, MJ (2021) Predictors of COVID-19 vaccine hesitancy in the UK household longitudinal study. Brain, Behavior, and Immunity 94, 41–50.10.1016/j.bbi.2021.03.008CrossRefGoogle Scholar
Schultz, NH, Sørvoll, IH, Michelsen, AE, Munthe, LA, Lund-Johansen, F, Ahlen, MT, Wiedmann, M, Aamodt, AH, Skattør, TH and Tjønnfjord, GE (2021) Thrombosis and thrombocytopenia after ChAdOx1 nCoV-19 vaccination. New England Journal of Medicine.CrossRefGoogle Scholar
Schwarzinger, M, Watson, V, Arwidson, P, Alla, F and Luchini, S (2021) COVID-19 vaccine hesitancy in a representative working-age population in France: a survey experiment based on vaccine characteristics. The Lancet Public Health 6 (4), e210–e221.CrossRefGoogle Scholar
Sønderskov, KM, Dinesen, PT and Østergaard, SD (2021) Sustained COVID-19 vaccine willingness after safety concerns over the Oxford-AstraZeneca vaccine. Danish Medical Journal 68, A03210292.Google ScholarPubMed
Sønderskov, KM, Dinesen, PT, Santini, ZI and Østergaard, SD (2020a) The depressive state of Denmark during the COVID-19 pandemic. Acta neuropsychiatrica 32, 226–228.CrossRefGoogle ScholarPubMed
Sønderskov, KM, Dinesen, PT, Santini, ZI and Østergaard, SD (2020b) Increased psychological well-being after the apex of the COVID-19 pandemic. Acta neuropsychiatrica 32, 277–279.CrossRefGoogle ScholarPubMed
Sønderskov, KM, Dinesen, PT, Vistisen, HT and Østergaard, SD (2021) Variation in psychological well-being and symptoms of anxiety and depression during the COVID-19 Pandemic: results from a 3-wave panel survey. Acta Neuropsychiatrica 33(3), 156–159.CrossRefGoogle Scholar
Wang, Q, Xu, R and Volkow, ND (2021) Increased risk of COVID-19 infection and mortality in people with mental disorders: analysis from electronic health records in the United States. World Psychiatry 20, 124–130.CrossRefGoogle ScholarPubMed
Wise, J (2021) Covid-19: european countries suspend use of Oxford-AstraZeneca vaccine after reports of blood clots. BMJ 372, n699. CrossRefGoogle Scholar
Supplementary material: PDF

Jefsen et al. supplementary material

Jefsen et al. supplementary material

Download Jefsen et al. supplementary material(PDF)
PDF 414.2 KB