Hostname: page-component-6766d58669-bp2c4 Total loading time: 0 Render date: 2026-05-20T16:47:10.741Z Has data issue: false hasContentIssue false
  • English
  • Français

Adenoid cystic carcinoma of the salivary glands: Clinicopathological survey of 51 patients

Published online by Cambridge University Press:  29 June 2007

V. N. Koka ,
R. M. Tiwari ,
I. van der Waal ,
G. B. Snow ,
J. Nauta ,
A. B. M. F. Karim  and
A. H. Tierie
V. N. Koka
Affiliation:
Postgraduate observer, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
R. M. Tiwari*
Affiliation:
Department of Otolaryngology/ Head and Neck Surgery, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
I. van der Waal
Affiliation:
Department of Oral Pathology, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
G. B. Snow
Affiliation:
Department of Otolaryngology/ Head and Neck Surgery, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
J. Nauta
Affiliation:
Department of Statistics, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
A. B. M. F. Karim
Affiliation:
Department of Radiotherapy, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
A. H. Tierie
Affiliation:
Department of Radiotherapy, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
*
R. M. Tiwari, M.S., F.R.C.S., PhD, Department of Otolaryngology/Head and Neck Surgery, Free University Hospital, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
Get access Rights & Permissions [Opens in a new window]

Abstract

A clinicopathological study of 51 cases of adenoid cystic carcinoma in the head and neck region seen over a period of 20 years is presented. The correlation between various histological features and their impact on the results is attempted. Longterm results with respect to loco-regional recurrences, distant metastases and survival with various modalities of therapy are presented. Although this is a small series, radical surgery in keeping with the aim of avoiding undue mutilation, thus preserving the quality of life, followed by a full course of radiotherapy has been the mainstay of treatment and the results here presented justify this approach.

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 103 , Issue 7 , July 1989 , pp. 675 - 679
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Allen, M. S. and Marsch, W. L. (1976) Lymph node involvement by direct extension in adenoid cystic carcinoma. Cancer 38: 2017–2021.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
Batsakis, J. G. and Regezi, J. A. (1979) The pathology of head and neck tumours. Salivary glands. Part 4, Head and Neck Surgery 1: 340–349.CrossRefGoogle ScholarPubMed
Blanck, C., Eneroth, C. M., Jacobsson, F. and Jakobsson, P. A. (1967) Adenoid cystic carcinoma of the parotid gland. Acta Radiologica 6: 177–196.CrossRefGoogle ScholarPubMed
Conley, J. and Dingman, D. L. (1974) Adenoid cystic carcinoma in the head and neck (cylindroma). Archives of Otolaryngology 100: 81–90.CrossRefGoogle ScholarPubMed
Eby, L. S., Johnson, D. S., Baker, H. W. (1972) Adenoid cystic carcinoma of the head and neck. Cancer 29: 1160–1166.3.0.CO;2-1>CrossRefGoogle ScholarPubMed
Eneroth, C. M. and Hjertman, L. (1966) Adenoidcystic carcinoma of the submandibular gland. Laryngoscope 76: 1639–1659.CrossRefGoogle Scholar
Eneroth, C. M., Hjertman, L. and Moberger, G. (1968) Adenoid cystic carcinoma of the palate. Acta Otolaryngologica 66: 248–260.CrossRefGoogle ScholarPubMed
Foote, F. W. and Frazell, E. L. (1953) Tumours of the major salivary glands. Cancer 6: 1065–1133.3.0.CO;2-0>CrossRefGoogle ScholarPubMed
Grahne, B., Lauren, C. and Holsti, L. R. (1977) Clinical and histological malignancy of adenoid cystic carcinoma. Journal of Laryngology and Otology 90: 743–749.CrossRefGoogle Scholar
Migilianico, L., Eschwege, F., Marandas, P. and Wibault, P. (1987) Cervicofacial adenoid cystic carcinoma study of 102 cases. International Journal of Radiation, Oncology, Biology, Physics 13: 673–678.CrossRefGoogle Scholar
Moran, J. J., Becker, S. M., Brady, L. W. and Rambo, V. B. (1961) Adenoid cystic carcinoma. Cancer 14: 1235–1250.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
Perzin, K. H., Gullane, P. and Clairmont, A. C. (1978) Adenoid cystic carcinomas arising in salivary glands. Cancer 42: 265–282.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Smith, L. C., Lane, N., Rankow, R. M. (1965) Cylindroma (Adenoid cystic carcinoma). American Journal of Surgery 110: 519–526.CrossRefGoogle ScholarPubMed
Spiro, R. H., Koss, L. G., Hadjn, S. I. and Strong, E. W. (1973) Tumours of minor salivary origin. Cancer 31: 117–129.3.0.CO;2-7>CrossRefGoogle ScholarPubMed
Spiro, R. H., Huvos, A. G. and Strong, E. W. (1974) Adenoid cystic carcinoma of salivary origin. American Journal of Surgery 128: 512–520.CrossRefGoogle ScholarPubMed
Szanto, P. A., Luna, M. A., Tortokdo, M. E. and White, R. A. (1984) Histologic grade of adenoid cystic carcinoma of the salivary gland. Cancer 54: 1062–1069.3.0.CO;2-E>CrossRefGoogle Scholar
Thackray, A. C. and Lucas, R. B. Tumours of the major salivary glands. Atlas of Tumor Pathology. 2nd. Series Fascide 10, Washington D.C., Armed Forces Institute of Pathology, 1984.Google Scholar
Vrielinck, L. J. G., Ostyn, F., van Damme, B., van den Bogaert, W. and Fossion, E. (1988) The significance of perineural spread in adenoid cystic carcinoma of the major and minor salivary glands. International Journal of Oral and Maxillofacial Surgery 17: 190–193.CrossRefGoogle ScholarPubMed