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Epistaxis and atorvastatin: is there an association and are clinicians aware? A retrospective audit of 100 patients

Published online by Cambridge University Press:  22 January 2020

E Heward  and
A S Lau
E Heward*
Affiliation:
ENT Department, Warrington and Halton NHS Foundation Trust, UK
A S Lau
Affiliation:
ENT Department, Warrington and Halton NHS Foundation Trust, UK
*
Author for correspondence: Mr Elliot Heward, ENT Department, Warrington and Halton NHS Foundation Trust, Lovely Lane, WarringtonWA5 1QG, UK E-mail: Elliotheward@doctors.org.uk
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Abstract

Objective

Epistaxis is a common ENT presentation. The British National Formulary lists epistaxis as a common side effect of atorvastatin. This study aimed to better understand the relationship between epistaxis and atorvastatin use, and determine whether ENT doctors are aware of its side effect profile.

Methods

A retrospective analysis over 10 months identified 100 individuals who presented to hospital with epistaxis. A questionnaire of 24 ENT registrars was undertaken.

Results

Of the 100 patients admitted with epistaxis, 27 were receiving atorvastatin and 21 simvastatin. None of the 24 ENT registrars were aware that epistaxis was a listed common side effect of atorvastatin.

Conclusion

There was no apparent difference in the proportion of patients admitted with epistaxis taking atorvastatin versus simvastatin. Epistaxis is an unknown side effect of atorvastatin; doctors have an obligation to be aware of the pharmaceutical literature and to consider alternatives, particularly in re-admissions cases.

Keywords

EpistaxisAtorvastatinHydroxymethylglutaryl-CoA Reductase InhibitorsNasopharyngitis

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 2 , February 2020 , pp. 138 - 140
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Mr E Heward takes responsibility for the integrity of the content of the paper

Presented at the British Academic Conference in Otolaryngology (‘BACO’) International meeting, 4–6 July 2018, Manchester, UK.

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