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Treatment of tinnitus by intratympanic instillation of lignocaine (lidocaine) 2 per cent through ventilation tubes

Published online by Cambridge University Press:  29 June 2007

Ludwig Podoshin ,
Milo Fradis  and
Yacov Ben David
Ludwig Podoshin*
Affiliation:
Haifa, Israel
Milo Fradis
Affiliation:
Haifa, Israel
Yacov Ben David
Affiliation:
Haifa, Israel
*
Prof. L. Podoshin, Dept of Otolaryngology, Bnai Zion Medical Centre, P.O.B. 4940, Haifa 31048, Israel
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Abstract

Idiopathic subjective tinnitus (1ST) is one of the most obscure otological pathologies. This paper presents the results of treating 1ST by intratympanic instillation of lignocaine (lidocaine) 2 per cent through a grommet, for five weekly courses. Fifty-two patients suffering from intractable tinnitus entered this therapeutic trial, but only nine finished all five courses. In one patient, the tinnitus was almost completely abolished, but in all the nine patients the decompensated tinnitus changed to a compensated one. We suggest this mode of treatment for patients that were previously treated by drugs, acupuncture and biofeedback, with disappointing results.Patients should be warned about the side effects of vertigo and vomiting, which subsides gradually with every new instillation, and that the tinnitus may not disappear but will be alleviated, enabling them to cope more easily with the disease and lead a more normal life.

Keywords

TinnituslignocaineMiddle ear ventilation tubes

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 7 , July 1992 , pp. 603 - 606
Copyright
Copyright © JLO (1984) Limited 1992

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Footnotes

Presented at the IVth International Tinnitus Seminar, 27–30 August, 1991, Bordeaux, France.

References

Arnsdorf, M. F., Bigger, J. T. Jr (1972) Effect of lidocaine hydrochloride on membrane conductance in mammalian cardiac Purkinje fibres. Journal of Clinical Investigation, 51: 2252–2263.CrossRefGoogle Scholar
Bernard, C. G., Bohm, E. (1954) On the central effects of xylocaine with special reference to its influence on epileptic phenomena. Ada Physiologica Scandinavica, 31 (Supplement 114): 5–6.Google Scholar
Chung, D. Y., Gannon, R. P., Mason, L. (1984) Factors affecting the prevalence of tinnitus. Radiology, 23: 441–452.Google ScholarPubMed
Coles, R. A., Baskill, J. L., Sheldrake, J. B. (1985) Measurement and management of tinnitus. Journal of Laryngology and Otology, 92: 891–900.Google Scholar
Englesson, S., Larsson, B., Lindquist, N. G. (1976) Accumulation of 14C lidocaine in the inner ear. Ada Oto-Laryngologica, 82: 297–300.CrossRefGoogle ScholarPubMed
Fisch, U. (1970) Transtemporal surgery of the internal auditory canal: Report of 92 cases, techniques, indications and results. Advances in Otolaryngology, 17: 203–224.Google Scholar
Fradis, M., Podoshin, L., Ben-David, J., Reiner, B. (1985) Treatment of Meniere's disease by intratympanic injection with lidocaine. Archives of Otolaryngology, 111: 491–493.CrossRefGoogle ScholarPubMed
Gerjot, T. (1963) Intravenous xylocaine in the treatment of attacks of Meniere's disease. Acta Oto-Laryngologica, 80 (Supplement 188): 190–195.Google Scholar
Gerjot, T. (1976) Intravenous xylocaine in the treatment of attacks of Meniere's disease. Acta Oto-Laryngologica, 82: 301–302.Google Scholar
Israel, J. M., Connelly, T. S., McTigue, S. T. (1982) Lignocaine in the treatment of tinnitus auris. Archives of Otolaryngology, 108: 371–473.Google Scholar
Jovel, E., Mouncy, D. F., McGee, J. A. (1982) Auditory brainstem responses during systemic infusion of lidocaine. Archives of Otolaryngology, 108: 71–76.CrossRefGoogle Scholar
Lechtenberg, R., Shulman, A. (1984) Benzodiazepines in the treatment of tinnitus. Journal of Laryngology and Otology, (Supplement 9): 271–276.CrossRefGoogle Scholar
Medical Research Council's Institute of Hearing Research (1981) Epidemiology of Tinnitus. Ciba Foundation Symposium, 85: 16–34.Google Scholar
Musiek, F. E., Guerkink, N. A. (1982) Auditory brainstem response and central auditory test findings for patients with brainstem lesions. A preliminary report. Laryngoscope, 92: 891–900.CrossRefGoogle ScholarPubMed
Podoshin, L., Ben- David, Y., Fradis, M., Gerstel, R., Felner, H. (1991) Idiopathic subjective tinnitus treated by biofeedback, acupuncture and drug therapy. Ear, Nose and Throat Journal, (in press).Google ScholarPubMed
Sakata, E., Umeda, Y., Takahoshi, K., Ohtsui, K. (1976) Treatment of the cochlear tinnitus blocking therapy with 4 per cent lidocaine. Journal of Otolaryngology (Japan), 79: 741–745.Google Scholar
Sakata, E., Nakezarra, H., Iwashita, N. (1984) Therapy of tinnitus. Tympanic cavity infusion of lidocaine and steroid solution. Auris-Nasus-Larynx, 11(1): 11–18.CrossRefGoogle ScholarPubMed
Shea, J., Harell, M. (1978) Management of tinnitus auris with lidocaine and carbamazepine. Laryngoscope, 88: 1477–1484.CrossRefGoogle Scholar
Shea, J. (1984–5) Medical treatment of tinnitus with xylocaine and tocaine. Journal of Laryngology and Otology, (Supplement 9): 259–263.CrossRefGoogle Scholar
Silverstein, H. (1986) Transmeatal labyrinthectomy with and without cochleovestibular neurectomy. Laryngoscope, 86: 1777–1791.CrossRefGoogle Scholar