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Secretory IgA- and IgG-coated bacteria in chronically discharging ears

Published online by Cambridge University Press:  29 June 2007

Lars-Eric Stenfors  and
Simo Räisänen
Lars-Eric Stenfors*
Affiliation:
Department of Otolaryngology, University of Tromsö, Tromsö, Norway, and Central Hospital of Keski-Pohjanmaa, Kokkola, Finland.
Simo Räisänen
Affiliation:
Clinical Laboratory, Central Hospital of Keski-Pohjanmaa, Kokkola, Finland.
*
Lars-Eric Stenfors, M.D., Department of Otolaryngology, Central Hospital of Keski-Pohjanmaa, SF-67200 Kokkola, Finland.
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Abstract

SIgA- and IgG-coated bacteria obtained from 17 discharging middle ears (14 patients, 9 male, 5 female, age range from 1 to 79 years) were evaluated using an immunofluorescence assay. Simultaneously, quantitative and qualitative bacteriological analyses of the middle ear effusions (MEEs) were performed. MEEs containing Staphylococcus aureus harboured bacteria which were intensely coated with both SIgA and IgG antibodies. In contrast, MEEs containing Pseudomonas aeruginosa displayed minimal, if any, SIgA- and IgG-coated bacteria. Two young patients harboured bacteria (Haemophilus influenzae and S. aureus/Streptococcus pneumoniae, respectively) which were heavily coated with IgG, but not with SIgA. Immunoglobulin-coating of bacteria involved in otitis media is of the utmost importance in eradication of the infection.

Keywords

Otitis mediasuppurativeBacteria

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 7 , July 1991 , pp. 515 - 517
Copyright
Copyright © JLO (1984) Limited 1991

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