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Assessing psychological distress in cancer patients in intensive care: Validation of the intensive care psychological assessment tool in Mexico

Published online by Cambridge University Press:  28 August 2025

Mariana Flores-Constantino*
Affiliation:
Facultad de Psicología, Universidad Nacional Autónoma de México (UNAM), Mexico City, México
Francisco Lorenzo Juárez-García
Affiliation:
Investigaciones Epidemiológicas y Psicosociales, Instituto Nacional de Psiquiatría “Ramón de la Fuente Muñiz”, Mexico City, México
Adriana García-García
Affiliation:
Unidad de Cuidados Intensivos, Instituto Nacional de Cancerología, Mexico City, México
Tecelli Dominguez-Martínez
Affiliation:
Centro de Investigación en Salud Mental Global, Instituto Nacional de Psiquiatría “Ramón de la Fuente Muñiz”, Mexico City, México
Abigail Quintana-Sánchez
Affiliation:
Jefatura de Enfermería, Instituto Nacional de Cancerología, Mexico City, México
Nazira Calleja-Bello
Affiliation:
Facultad de Psicología, Universidad Nacional Autónoma de México (UNAM), Mexico City, México
Oscar Galindo-Vázquez
Affiliation:
Departamento de Salud Mental, Instituto Nacional de Cancerología, Mexico City, México
Manuel S. Ortiz
Affiliation:
Dirección del Programa de Doctorado en Psicología, Universidad de la Frontera, Temuco, Chile
Tania Estapé
Affiliation:
Departamento de Psicooncología, FEFOC Fundación Barcelona, Barcelona, Spain
Silvio A. Ñamendys-Silva
Affiliation:
Unidad de Cuidados Intensivos, Instituto Nacional de Cancerología, Mexico City, México
*
Corresponding author: Mariana Flores-Constantino; Email: fc.mariana@outlook.com
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Abstract

Background

Individuals admitted to the Intensive Care Unit (ICU) due to cancer frequently encounter cognitive impairment and alterations in their mental health, which engenders psychological distress and considerably impacts their quality of life. In Mexico, there is an imperative for valid and reliable clinical tools to identify these symptoms, to providing timely and appropriate psychological intervention.

Objectives

To determine the psychometric properties of the Intensive Care Psychological Assessment Tool (IPAT) in a Mexican population with cancer discharged from ICU.

Methods

A cross-sectional instrumental design with non-probability convenience sampling was employed. Data were collected between February 2023 and October 2024 with 75 people discharged from the ICU. Factor structure (confirmatory factor analysis), reliability (internal consistency), measurement invariance, and criteria validity (convergent, discriminant, and known-groups) were assessed. Patients were assessed during oncological hospitalization, following ICU.

Results

The participants were predominantly male, residing in the interior of the country, with an average age of 44 years (range 19–78, SD 16.21). Internal consistency results were deemed to be satisfactory (α = 0.78) for 9 items. The CFA indices were adequate [χ2 (gl) 27.436 (24), CMIN/DF 1.143, CFI 0.96, GFI 0.97, SRMR 0.036, RMSEA 0.044] as were the scalar invariance indices for invasive mechanical ventilation [CFI = 0.871; RMSEA = 0.058; χ2/gl = 20.519 (10)] and for gender, restricted invariance indices [CFI = 0.849; RMSEA = 0.068; χ2/gl = 23.302 (12)].

Significance of results

The Mexican version of the IPAT for people with cancer is a valid and reliable tool for use in oncology and critical care settings in Mexico. It is recommended for use at the time of discharge from the ICU, as it allows the identification of psychological distress for timely intervention. For future considerations, diverse clinical settings and patient populations should be explored to enhance the tool’s applicability and generalizability in the varied contexts of cancer in ICU.

Information

Type
Original Article
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press.
Figure 0

Table 1. Content validity ratio for the IPAT by 8 experts

Figure 1

Table 2. Aiken’s V of the IPAT by 8 experts

Figure 2

Table 3. Sociodemographic and clinical characteristics of a sample of 75 participants with cancer discharged from ICU

Figure 3

Table 4. Descriptive evaluation of the IPAT items

Figure 4

Figure 1. Final model of the Confirmatory Factor Analysis IPAT.

Figure 5

Table 5. Fit indices obtained for each one of the tested models

Figure 6

Table 6. Results of tests of measurement invariance by invasive mechanical ventilation

Figure 7

Table 7. Results of tests of measurement invariance by gender

Figure 8

Table 8. Criteria validity (IPAT and EORTC-QLQ-C30 subscales)

Figure 9

Table 9. Known-groups validity for IPAT scores, based on clinical variables

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