Hostname: page-component-6766d58669-r8qmj Total loading time: 0 Render date: 2026-05-21T11:37:19.945Z Has data issue: false hasContentIssue false
  • English
  • Français

The diagnosis and surgical management of olfactory neuroblastoma: The role of craniofacial resection

Published online by Cambridge University Press:  29 June 2007

P. Chapman ,
R. L. Carter  and
P. Clifford
P. Chapman*
Affiliation:
Head and Neck Unit and Department of Pathology, Royal Marsden Hospital and Institute of Cancer Research, London and Sutton.
R. L. Carter
Affiliation:
Head and Neck Unit and Department of Pathology, Royal Marsden Hospital and Institute of Cancer Research, London and Sutton.
P. Clifford
Affiliation:
Head and Neck Unit and Department of Pathology, Royal Marsden Hospital and Institute of Cancer Research, London and Sutton.
*
ENT Department, St. Mary's Hospital, Praed Street, Paddington, W2.
Get access Rights & Permissions [Opens in a new window]

Summary

The diagnosis and clinical management of olfactory neuroblastoma are discussed. Computerized tomography is a valuable means of assessing the pre-operative extent of disease and the efficacy of subsequent major surgery. The tissue diagnosis is facilitated by electron microscopy, demonstrating the presence of dence core vesicles and cytoplasmic filaments. Radiotherapy followed by craniofacial resection is the treatment of choice for olfactory neuroblastomas that are locally extensive at presentation.

Information

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 95 , Issue 8 , August 1981 , pp. 785 - 799
Copyright
Copyright © JLO (1984) Limited 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

REFERENCES

Backer, M. H., and Jacox, H. W. (1964) Radiology, 82, 77.CrossRefGoogle Scholar
Bailey, B. J., and Barton, S. (1915) Archives of Otolaryngology, 101, 1.Google Scholar
Baron, S. H. (1979) Laryngoscope, 89, 214.CrossRefGoogle Scholar
Becker, H., Grau, H., Hacker, H., and Ploder, K. W. (1978) Journal of Computer Assisted Tomography, 2, 113.CrossRefGoogle Scholar
Berger, L., Luc, , and Richard, , (1924) Bulletin de l'association Francais pour l'etude du cancer, 13, 410.Google Scholar
Berger, L., and Coutard, H. (1926) Bulletin de l'association Francais pour l'etude du cancer, 15, 404.Google Scholar
Cantrell, R. W., Ghorayeb, B. Y., and Fitzhugh, G. S. (1911) Annals of Otology, 86, 760.Google Scholar
Chaudry, A. P., Haar, J. G., Koul, A., and Nickerson, P. A. (1979) Cancer, 44, 564.3.0.CO;2-#>CrossRefGoogle Scholar
Clifford, P. (1977) Clinical Otolaryngology, 2, 115.CrossRefGoogle Scholar
Djalilian, M., Zujko, R. D., Weiland, L. H., Devine, K. D. (1977) Surgical Clinics of North America, 57, 751.CrossRefGoogle Scholar
Elkon, D., Hightower, S. L., Lim, M. L., Cantress, R. W., and Constable, W. C. (1979) Cancer, 44, 1087.3.0.CO;2-A>CrossRefGoogle Scholar
Elner, A., and Koch, H. (1974) Acta Otolaryngologica, 78, 270.CrossRefGoogle Scholar
Fitzhugh, G. S., Allen, M. S. Jr., Rucker, T. N., and Sprinkle, P. M. (1965) Archives of Otolaryngology, 81, 161.CrossRefGoogle Scholar
Hutter, R. V. P., Lewis, J. S., Foote, F. W. Jr., and Tollefsen, H. R. (1963) American Journal of Surgery, 106, 748.CrossRefGoogle Scholar
Judge, D. M., McGavran, M. H., and Trapukdi, S. (1976) Archives of Otolaryngology, 102, 97.CrossRefGoogle Scholar
Kadish, S., Goodman, M., and Wang, C. C. (1976) Cancer, 37, 1571.3.0.CO;2-L>CrossRefGoogle Scholar
Kahn, L. (1974) Human Pathology, 5, 364.CrossRefGoogle Scholar
Ketcham, A. S., Hoye, R. C., Van Buren, J. M., and Johnson, R. H. (1966) American Journal of Surgery, 122, 591.CrossRefGoogle Scholar
Kolze, V. (1968) Acta Otolaryngology, 65, 397.CrossRefGoogle Scholar
McGavran, M. H. (1916) Annals of Otology, Rhinology and Laryngology, 79, 547.CrossRefGoogle Scholar
Manelfe, C., Bonafe, A., Fabre, P., and Pessey, J-J. (1978) Journal of Computer Assisted Tomography, 2, 412.CrossRefGoogle Scholar
Micheau, C., Guerinot, F., Bohrun, C., and Brugere, J. (1975) Cancer, 35, 1309.3.0.CO;2-5>CrossRefGoogle Scholar
Micheau, C. (1977) Cancer, 40, 314.3.0.CO;2-7>CrossRefGoogle Scholar
Momose, K. J., Weber, A. L., and Goodman, M. L. (1978) Advances in Oto-Rhino-Laryngology, 24, 166.CrossRefGoogle Scholar
Oberman, H. A., and Rice, D. H. (1976) Cancer, 38, 2494.3.0.CO;2-U>CrossRefGoogle Scholar
Obert, G. J., Devine, K. D., and McDonald, J. R. (1960) Cancer, 13, 205.3.0.CO;2-G>CrossRefGoogle Scholar
Osamura, R. Y., and Fine, G. (1976) Cancer, 38, 173.3.0.CO;2-W>CrossRefGoogle Scholar
Portmann, G., Bonnard, , and Moreau, (1928) Acta Otolaryngologica Stockholm, 13, 52.CrossRefGoogle Scholar
Robinson, E., and Solitar, G. B. (1966) Journal of Neurosurgery, 25, 133.CrossRefGoogle Scholar
Schall, L. A., and Lineback, M. (1951) Annals of Otology, Rhinology and Laryngology, 60, 221.CrossRefGoogle Scholar
Schenk, N. L., and Ogura, J. H. (1972) Archives of Otolaryngology, 96, 322.CrossRefGoogle Scholar
Taxy, J. B., and Hidvego, D. F. (1977) Cancer, 39, 131.3.0.CO;2-G>CrossRefGoogle Scholar