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Meta-analytic studies of the glial cell marker TSPO in psychosis – a question of apples and pears?: A commentary on ‘Neuroinflammation in schizophrenia: metaanalysis of in-vivo microglial imaging’ by Marques et al. – ERRATUM

Published online by Cambridge University Press:  30 April 2019

P. Plavén-Sigray  and
S. Cervenka
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Abstract

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Information

Type
Erratum
Information
Psychological Medicine , Volume 49 , Issue 9 , July 2019 , pp. 1583 - 1584
Copyright
Copyright © Cambridge University Press 2019 

The above mentioned article was published in Psychological Medicine with the captions for figs. 1 and 2 inadvertently swapped. The correct figures and their accompanying captions are listed below:

Fig. 1.

The magnitude of the effect size and the measurement error of the studies included in the (R)-[11C]PK11195 meta-analysis by Marques et al. (left figure) show a high degree of association (r = 0.9). Potential reasons for such a shape are publication bias or inflated effect sizes in studies with unreliable outcomes and small sample sizes, leading to an inflated overall effect size. When Marques et al. corrected for this bias, the difference between healthy controls and patients with psychosis or schizophrenia was no longer statistically significant (right figure).

Fig. 2.

The different outcomes used by the studies included in the (R)-[11C]PK11195 meta-analysis by Marques et al. show little to no association with one another. This figure presents pooled data from 12 (R)-[11C]PK11195 examinations of healthy controls from a set of different regions (whole gray matter, thalamus, frontal cortex, hippocampus and striatum).

Cambridge University Press apologises for this error.

References

Plavén-Sigray, P & Cervenka, S (2019) Meta-analytic studies of the glial cell marker TSPO in psychosis – a question of apples and pears?: A commentary on ‘Neuroinflammation in schizophrenia: metaanalysis of in-vivo microglial imaging’ by Marques et al. Psychological Medicine, 1–5. Cambridge University Press.Google Scholar
Figure 0

Fig. 1. The magnitude of the effect size and the measurement error of the studies included in the (R)-[11C]PK11195 meta-analysis by Marques et al. (left figure) show a high degree of association (r = 0.9). Potential reasons for such a shape are publication bias or inflated effect sizes in studies with unreliable outcomes and small sample sizes, leading to an inflated overall effect size. When Marques et al. corrected for this bias, the difference between healthy controls and patients with psychosis or schizophrenia was no longer statistically significant (right figure).

Figure 1

Fig. 2. The different outcomes used by the studies included in the (R)-[11C]PK11195 meta-analysis by Marques et al. show little to no association with one another. This figure presents pooled data from 12 (R)-[11C]PK11195 examinations of healthy controls from a set of different regions (whole gray matter, thalamus, frontal cortex, hippocampus and striatum).