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Oral cavity squamous cell carcinoma metastasis to the submandibular gland

Published online by Cambridge University Press:  13 October 2011

T K Naidu ,
S K Naidoo  and
P K Ramdial
T K Naidu*
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
S K Naidoo
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
P K Ramdial
Affiliation:
Department of Anatomical Pathology, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa Department of Anatomical Pathology, National Health Laboratory Service, Durban, South Africa
*
Address for correspondence: Dr T K Naidu, Department of Otorhinolaryngology, Head and Neck Surgery, 4th Floor, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Umbilo, Durban 4013, KwaZulu-Natal, Republic of South Africa Fax: +2731 2604480 E-mail: tesuven@gmail.com
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Abstract

Introduction:

This study aimed to evaluate the incidence of submandibular gland metastases in cases of oral cavity squamous cell carcinoma.

Methods:

Sixty-nine patients treated between 1 January 2004 and 30 June 2009 were retrospectively reviewed. Patients were treated with wide local excision of the primary tumour, plus simultaneous neck dissection and reconstruction if required.

Results:

Of 69 submandibular glands from 46 men and 23 women (mean age, 58 years), 43 (62.3 per cent) had advanced, tumour stage three or four lesions. Histopathological reappraisal of all submandibular glands demonstrated an absence of metastatic spread. Only 2/69 (2.9 per cent) submandibular glands demonstrated ipsilateral contiguous tumour involvement.

Conclusion:

This study demonstrated an absence of metastasis to the submandibular gland from oral cavity squamous cell carcinoma. Patients with early stage oral cavity squamous cell carcinoma and with a pre-operative node stage zero neck may be candidates for preservation of the submandibular gland during neck dissection.

Keywords

Carcinoma, Squamous CellSubmandibular GlandNeoplasm MetastasisMouthNeck DissectionXerostomia

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 3 , March 2012 , pp. 279 - 284
Copyright
Copyright © JLO (1984) Limited 2011

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