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Pathology of the eustachian tube in otitis media: an electron microscopic study

Published online by Cambridge University Press:  29 June 2007

Samy Elwany
Samy Elwany*
Affiliation:
Alexandria, Egypt
*
Professor Sam Elwany, M.D., Alexandria Medical School, P.O. Box 267, Sidi Gaber, Alexandria, Egypt.
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Abstract

The ultrastructure of the mucosa of the eustachian tube was studied in four temporal bones showing tympanosclerosis, cholesteatoma, otitic meningitis and a grafted tympanic membrane (tympanoplasty). The mucosa of tube was abnormal in the four cases confirming the relationship between the state of the eustachian tube and the inflammatory process in the middle ear. The observed abnormalities included: ciliary loss, abnormal ciliary morphology and motility, oedema of the microvilli, hyperplasia of the goblet cells and the seromucinous acini, desquamation of the non-ciliated cells and appearance of mast cells in the lamina propria of the tube. Ciliary changes were the most frequent abnormalities and the morphological changes, in general, were fewest in the case of healed tympanoplasty. The pathophysiology of the morphological changes was discussed and correlated with the disease in the middle ear.

Keywords

Eustachian tubeOtitis mediaMicroscopy, electron
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 7 , July 1993 , pp. 651 - 655
Copyright
Copyright © JLO (1984) Limited 1993

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References

Birch, L., Elbrand, O. (1986) Mucociliary function in the nasal cavity of children and adolescents with cholesteatoma. Clinical Otolaryngology 11: 15–19CrossRefGoogle ScholarPubMed
Dudley, J. P., Cherry, J. D., Eisner, L. (1982) Scanning electron microscopic study of non-beating cilia. Annals of Otology, Rhinology, and Laryngology 91: 612–614CrossRefGoogle Scholar
Duncan, J. R., Ramsey, F. K. (1965) Fine structural changes in the porcine nasal ciliated epithelial cells produced by bordetella bronchoseptica rhinitis. American Journal of Pathology 47: 601–612Google Scholar
Elwany, S., Talaat, M., Talaat, M., Helmy, A. (1983) Allergic nasal mucosa following topical treatment with beclometazone dipropionate (Bdp) aerosol. The Journal of Laryngology and Otology 97: 165–176CrossRefGoogle Scholar
Elwany, S. (1985) Delayed ultrastructural radiation-induced changes in the human mesotympanic middle ear mucosa. The Journal of Laryngology and Otology 99: 343–353CrossRefGoogle ScholarPubMed
Elwany, S., Bumsted, R. (1987) Ultrastructural observations on vasomotor rhinitis. ORL 49: 199–205CrossRefGoogle ScholarPubMed
Elwany, S. (1990) Tympanic neurectomy: its effects on the seromucinous glands of the middle ear of cats. ORL 52: 292–296CrossRefGoogle ScholarPubMed
Friedmann, I., Biud, E. S. (1971) Ciliary structure, ciliary genesis microvilli. Larynoscope 81: 1852–1968CrossRefGoogle Scholar
Friedmann, I., Bennett, M. H. (1986) In Systemic Pathology of Nose, Throat and Ear (Friedmann, I., ed.) Churchill-Livingstone, London, p. 3–14.Google Scholar
Harada, Y. (1977) Scanning electron microscopic study on the distribution of epithelial cell in the eustachian tube. Ada Otolaryngologica 83: 284–288CrossRefGoogle ScholarPubMed
Harada, Y. (1983) Atlas of the Ear by Scanning Electron Microscopy, MTP Press Ltd, Lancaste, p. 25–30.Google Scholar
Hentzer, E. (1970) Ultrastructure of the normal mucosa in the human middle ear, mastoid cavities and eustachian tube. Annals of Otology, Rhinology and Laryngology 79: 1143–1147.CrossRefGoogle ScholarPubMed
Lim, D. J., Paparella, M. M., Kimura, R. S. (1967) Ultrastructure of the eustachian tube and middle ear mucosa in guinea pigs. Ada Otolaryngologica 63: 425–429CrossRefGoogle Scholar
Lim, D. J. (1974) Functional morphology of the lining membrane of the middle ear and eustachian tube. Annals of Otology, Rhinology and Laryngology 83 (suppl. 11): 5–26.CrossRefGoogle ScholarPubMed
Ohashi, Y., Nakai, Yyy, Ileoka, H., Koshimo, H., Esaki, S. (1987) Effects of bacterial endotoxins on the ciliary activity in the in vitro middle ear mucosa. Acta Otolaryngologica 104: 495–499CrossRefGoogle ScholarPubMed
Sadé, J. (1979) In Secretory Otitis Media and its sequels. (Sade, J., ed.), Churchill-Livingstone, London p.184.Google Scholar
Shimada, T., Lim, D. (1972) Distribution of ciliated cells in the human middle ear. Annals of Otology, Rhinology and Laryngology 81: 203–207.CrossRefGoogle ScholarPubMed
Smith, C., Vernon, J. (1976) Handbook of auditory and vestibular research methods. Charles C. Thomas Springfields.Google Scholar
Toppozada, H., Michaels, L., Toppozada, M., El-Ghazzawi, I., Talaat, M., Elwany, S. (1982) The human respiratory nasal mucosa in pregnancy. The Journal of Laryngology and Otology 96: 613–626CrossRefGoogle ScholarPubMed
Tos, M. (1979) In Secretory Otitis Media and its sequels. (Sade, J., ed.) Churchill-Livingstone, London p. 36–63.Google Scholar
Von Mecklenburg, C. V., Merke, U., Hakansson, C. H., Toremalm, N. G. (1974) Morphological changes in ciliary cells due to heat exposure. A scanning electron microscopic study. Cell and Tissue Research 148: 45–56Google ScholarPubMed