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Sinonasal hybrid tumour involving the anterior skull base

Published online by Cambridge University Press:  12 July 2007

A Mazita ,
B S Gendeh  and
A I Zainal
A Mazita*
Affiliation:
Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
B S Gendeh
Affiliation:
Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
A I Zainal
Affiliation:
Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
*
Address for correspondence: Dr Mazita Ami, Department of ORL-HNS, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia. Fax: 603 91737840 E-mail: mazitaami@yahoo.com
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Abstract

Objective:

We report a rare case of sinonasal hybrid tumour within an inverted papilloma.

Method:

The patient's case history and course of management are presented. The relevant medical literature are reviewed and discussed.

Results:

A 60-year-old man presented with unilateral nasal obstruction associated with anosmia. An ENT examination revealed a unilateral, left nasal mass. A provisional diagnosis of inverted papilloma was made. The patient underwent a transnasal endoscopic excision of the tumour, which was unfortunately complicated by a cerebrospinal fluid leak. Further treatment of this patient is described. We highlight the features of associated malignancy in inverted papilloma, and the importance of thorough histopathological examination of tissue specimens.

Conclusion:

Treatment of inverted papilloma with limited involvement of the skull base can be successfully achieved by endoscopic excision. A high index of clinical suspicion, together with meticulous histopathological examination, will enable diagnosis of associated malignancy. This will ensure that appropriate adjuvant treatment is given, resulting in a good clinical outcome.

Keywords

Hybrid TumourInverted PapillomaParanasal Sinus NeoplasmsEndoscopes

Information

Type
Clinical Record
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 8 , August 2008 , pp. 861 - 863
Copyright
Copyright © JLO (1984) Limited 2008

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Footnotes

Presented at the 26th International Symposium on Infection and Allergy of the Nose. 1–4 February 2007, Kuala Lumpur, Malaysia.

References

1Nachtigal, D, Yoskovitch, A, Frenkiel, S, Braverman, I, Rochon, L. Unique characteristics of malignant schneiderian papilloma. Otolaryngol Head Neck Surg 1999;121:766–71CrossRefGoogle ScholarPubMed
2Bhaya, MH, Har-El, G. The biology and histopathology of inverted papillomas. Operative techniques in Otolaryngolgy – Head and Neck Surgery 1999;10:68–70CrossRefGoogle Scholar
3Batsakis, JG, Suarez, P, El-Naggar, AK. Proliferative verrucous leukoplakia and its related lesions. Oral Oncol 1999;35:3549CrossRefGoogle ScholarPubMed
4Orvidas, LJ, Lewis, JE, Olsen, KD, Weiner, JS. Intranasal verrucous carcinoma: relationship to inverting papilloma and human papillomavirus. Laryngoscope 1999;109:371–5CrossRefGoogle ScholarPubMed
5Go, JH, Oh, YL, Ko, YH. Hybrid verrucous squamous cell carcinoma of sinonasal tract: a case report. J Korean Med Sci 1998;13:662–4CrossRefGoogle ScholarPubMed
6Batsakis, JG, Suarez, P. Schneiderian papillomas and carcinomas: a review. Advances in Anatomic Pathology 2001;8:53–64CrossRefGoogle ScholarPubMed
7Suda, Y, Hanamura, Y, Kasano, F, Kashima, N. Verrucous carcinoma of the nasal cavity: a case report [in Japanese]. Nippon Jibiinkoka Gakkai Kaiho 2003;106:156–9CrossRefGoogle ScholarPubMed
8Letichevsky, V, Talmon, Y, Samet, A, Cohen, Y. Verrucous carcinoma of the nose and maxillary sinus [in Hebrew]. Harefuah 2001;140:706–8Google ScholarPubMed
9Pasquini, E, Sciarretta, V, Farneti, G, Modugno, GC, Ceroni, AR. Inverted papilloma: report of 89 cases. Am J Otolaryngol 2004;25:178–85CrossRefGoogle ScholarPubMed
10Kraft, M, Simmen, D, Kaufmann, T, Holzmann, D. Long term results of endonasal sinus surgery in sinonasal papillomas. Laryngoscope 2003:113:1541–47CrossRefGoogle ScholarPubMed
11Lawson, W, Kaufman, MR, Biller, HF. Treatment outcomes in the management of inverted papilloma: an analysis of 160 cases. Laryngoscope 2003:113:1548–56CrossRefGoogle ScholarPubMed
12Gomez, JA, Mendenhall, WM, Tannehill, SP, Stringer, SP, Cassisi, NJ. Radiation therapy in inverted papillomas of the nasal cavity and paranasal sinuses. Am J Otolaryngol 2000;121:174–8CrossRefGoogle Scholar