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Plexiform schwannoma of the cheek

Published online by Cambridge University Press:  29 June 2007

Giacinto M. Mannarà ,
Filippo C. La Rosa  and
Filippo Marino
Giacinto M. Mannarà*
Affiliation:
Department of OtolaryngologyUniversity of Padua, Padua, Italy.
Filippo C. La Rosa
Affiliation:
Department of OtolaryngologyUniversity of Padua, Padua, Italy.
Filippo Marino
Affiliation:
Department of PathlogyUniversity of Padua, Padua, Italy.
*
Address for correspondence: Giacinto M. Mannarà, M.D., Department of Otolaryngology – Head and Neck Surgery, Nuovo Policlinico, Via Giustiniani 2, 35100 Padua, Italy. Fax: 0039 49 8752266
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Abstract

We present a case of subcutaneous plexiform schwannoma, a rare benign peripheral nerve sheath tumour characterized by a multinodular and plexiform growth pattern. A review of the literature was performed to identify the relationship between plexiform schwannoma and neurofibromatosis types 1 and 2, and schwannomatosis.

It is also important to distinguish plexiform schwannoma from plexiform neurofibroma, a particular type 1 neurofibromatosis lesion, because of the propensity of the latter for malignant degeneration.

Keywords

SchwannomaNeurofibromatosis

Information

Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 11 , November 1999 , pp. 1034 - 1035
Copyright
Copyright © JLO (1984) Limited 1999

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References

Barbosa, J., Hansen, L. S. (1984) Solitary multilobular schwannoma of the oral cavity. Journal of Oral Medicine 39: 232–235.Google ScholarPubMed
Harkin, J. C., Arrington, J. H., Reed, R. J. (1978) Benign plexiform schwannoma, a lesion distinct from plexiform neurofibroma. Journal of Neuropathology and Experimental Neurology 37: 622. Abstract.CrossRefGoogle Scholar
Honda, M., Arai, E., Sawada, S., Ohta, A., Niimura, M. (1995) Neurofibromatosis 2 and neurilemmomatosis genes are identical. Journal of Investigative Dermatology 104: 74–77.CrossRefGoogle ScholarPubMed
Ishida, T., Kuroda, M., Motoi, T., Oka, T., Imamura, T., Machinami, R. (1998) Phenotypic diversity of neurofibromatosis 2: association with plexiform schwannoma. Histopathology 32: 264–270.CrossRefGoogle ScholarPubMed
Iwashita, T., Enjoji, M. (1987) Plexiform neurilemmoma: a clinicopathological and immunohistochemical analysis of 23 tumours from 20 patients. Virchows Archiv A Pathological Anatomy and Histopathology 411: 305–309.CrossRefGoogle ScholarPubMed
Masson, P. (1970) Human Tumours: Histology, Diagnosis, and Technique. 2nd Edition. Wayne State University Press, Detroit, p 1103.Google Scholar
Murata, Y., Kumano, K., Ugai, K., Ijichi, A., Taomoto, K., Tani, M. (1991) Neurilemmomatosis. British Journal of Dermatology 125: 466–468.Google Scholar
Purcell, S. M., Dixon, S. L. (1989) Schwannomatosis: an unusual variant of neurofibromatosis or a distinct entity? Archives of Dermatology 125: 390–393.CrossRefGoogle ScholarPubMed
Reith, J. D., Goldblum, J. R. (1996) Multiple cutaneous plexiform schwannomas. Report of a case and review of the literature with particular reference to the association with types 1 and 2 neurofibromatosis and schwannomatosis. Archives of Pathology and Laboratory Medicine 120: 399–401.Google Scholar
Rongioletti, F., Drago, F., Rebora, A. (1989) Multiple cutaneous plexiform schwannomas with tumours of the central nervous system. Archives of Dermatology 125: 431–432.CrossRefGoogle Scholar
Shishiba, T., Niimura, M., Ohtsuka, F., Tsuru, N. (1984) Multiple cutaneous neurilemmomas as a skin manifestation of neurilemmomatosis. Journal of the American Academy of Dermatology 10: 744–754.CrossRefGoogle ScholarPubMed
Val-Bernal, J. F., Figols, J., Vázquez-Barquero, A. (1995) Cutaneous plexiform schwannoma associated with neurofibormatosis type 2. Cancer 76: 1181–1186.3.0.CO;2-P>CrossRefGoogle ScholarPubMed
Woodruff, J. M., Funkhouser, J. W., Marshall, M. L., Thompson, N. J., Godwin, T. A., Erlandson, R. A. (1983) Plexiform (multinodular) schwannoma. A tumour simulating the plexiform neurofibroma. American Journal of Surgical Pathology 7: 691–697.CrossRefGoogle ScholarPubMed