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Rheological properties of engineered protein polymer networks

Published online by Cambridge University Press:  10 December 2020

Winnie H. Shi
Affiliation:
Department of Chemical and Biomolecular Engineering, Rice University, USA; whs2@rice.edu
Taniya M.S.K. Pathiranage
Affiliation:
Rice University, USA; tk37@rice.edu
Amanda B. Marciel
Affiliation:
Department of Chemical and Biomolecular Engineering, Rice University, USA; Am152@rice.edu
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Abstract

The linear and nonlinear mechanical properties of recombinant protein polymer networks are reviewed, with particular emphasis on how to tune elastic and dissipative behavior through selection of cross-linking strategy. The design strategies used to produce modular recombinant protein polymer networks through chemical or physical cross-linking will be discussed. In particular, we will highlight how key parameters such as polymer concentration, molecular weight, architecture, cross-link density, and association strength influence mechanics of protein polymer networks. Tuning these parameters enables control of viscoelastic properties and formation of materials with applications in tissue engineering, drug delivery, and sustainable self-healing materials.

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Type
Engineered Proteins as Multifunctional Materials
Copyright
Copyright © The Author(s), 2020, published on behalf of Materials Research Society by Cambridge University Press

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