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Accepted manuscript

Oleanolic Acid Attenuates Ovarian Aging in Laying Hens via Inhibition of the cGAS–STING Pathway

Published online by Cambridge University Press:  31 March 2026

Feng-Jie Hu ,
Chen Zhao ,
Ming-Hui Xiao ,
Huan Chang ,
Xiao-Die Lin ,
Bo-Yuan Ji ,
Yu Zhao ,
Kai-Yong Yao ,
Chen-Xing Liu  and
Zhi-Hong Pan
...Show all authors
Feng-Jie Hu
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Chen Zhao
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Ming-Hui Xiao
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Huan Chang
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Xiao-Die Lin
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Bo-Yuan Ji
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Yu Zhao
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
Kai-Yong Yao
Affiliation:
Zhejiang Seed Industry Group Xinchuang Biological Breeding Co., Ltd, Hangzhou, 311225, China
Chen-Xing Liu
Affiliation:
Food Science Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China
Zhi-Hong Pan
Affiliation:
Lanhai Ecological Agriculture (Hangzhou) Co, Ltd, Hangzhou, 311402, China
Sithixay Xayavong
Affiliation:
Savannakhet University, Kaysone Phomvihane City, Savannakhet Province, 13000, Lao PDR
Ying-Ping Xiao*
Affiliation:
State Key Laboratory for Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China
Xing-Xing Dai*
Affiliation:
Department of Obstetrics and Gynecology, Center for Reproductive Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, 322000, China
Jie Cai*
Affiliation:
Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China Zhejiang Provincial Engineering Research Center of Animal Biological Products, Zhejiang University Center for Veterinary Sciences, Hangzhou, 310058, China
*
Corresponding author: Jie Cai, Email: zjcaijie@zju.edu.cn, Xing-Xing Dai, Email: daixx1992@zju.edu.cn, Ying-ping Xiao, Email: xiaoyp@zaas.ac.cn
Corresponding author: Jie Cai, Email: zjcaijie@zju.edu.cn, Xing-Xing Dai, Email: daixx1992@zju.edu.cn, Ying-ping Xiao, Email: xiaoyp@zaas.ac.cn
Corresponding author: Jie Cai, Email: zjcaijie@zju.edu.cn, Xing-Xing Dai, Email: daixx1992@zju.edu.cn, Ying-ping Xiao, Email: xiaoyp@zaas.ac.cn
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Information

Type
Research Article
Information
Animal Nutriomics , Accepted manuscript , pp. 1 - 43
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2026. Published by Cambridge University Press on behalf of Zhejiang University and Zhejiang University Press.