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Examining suicide literacy among emerging adult medical students in Puerto Rico

Published online by Cambridge University Press:  24 March 2026

Fabio Barreto-Ayes*
Affiliation:
Ponce Health Sciences University School of Behavioral & Brain Science , Puerto Rico
Estefany Velez-Baez
Affiliation:
Ponce Health Sciences University , Puerto Rico
Erik Velez-Perez
Affiliation:
Ponce Health Sciences University , Puerto Rico
Elina Aguilar-Jiménez
Affiliation:
Ponce Health Sciences University School of Behavioral & Brain Science , Puerto Rico
Mario Bermonti-Pérez
Affiliation:
Ponce Health Sciences University , Puerto Rico
Norka Polanco-Frontera
Affiliation:
Ponce Health Sciences University , Puerto Rico
Eliut Rivera-Segarra
Affiliation:
Ponce Health Sciences University , Puerto Rico
*
Corresponding author: Fabio Barreto-Ayes; Email: fbarreto22@stu.psm.edu
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Abstract

Suicide is a leading cause of death among emerging adults (EAs) worldwide, yet suicide literacy (SL) in this population remains understudied, particularly in Puerto Rico (PR). This study assessed SL among EAs enrolled at a medical school in PR and explored its association with knowing someone who had experienced suicidal ideation (SI) or attempted suicide (SA). A cross-sectional study was conducted with 102 participants aged 21–28 years. Participants completed a sociodemographic questionnaire and the Literacy of Suicide Scale (LOSS). The mean LOSS score was 19.25 out of 27 (71.3%), with a domain-specific pattern characterized by relatively higher performance in the treatment/prevention and lower performance in the recognition of signs and symptoms. Regression analysis revealed that knowing someone with lived experience of SI/SA was associated with higher SL scores, while gender was not significantly associated. These findings suggest that, although medical students may have general knowledge about suicide prevention, they may struggle to identify early warning signs. This study contributes to the emergent literature on SL among EAs globally and highlights the need for further research on SL domain-specific strengths and weaknesses.

Information

Type
Research Article
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NC
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial licence (http://creativecommons.org/licenses/by-nc/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use.
Copyright
© The Author(s), 2026. Published by Cambridge University Press
Figure 0

Table 1. Sociodemographic characteristics of participants

Figure 1

Table 2. Performance on different themes of the literacy of suicide (combined cohorts)

Figure 2

Table 3. Linear regression analysis predicting suicide literacy, adjusted by gender

Author comment: Examining suicide literacy among emerging adult medical students in Puerto Rico — R0/PR1

Comments

August 20, 2025

Editor-in-Chief

Cambridge Prisms: Global Mental Health

Cambridge University Press

Dear Editor,

Please find enclosed our manuscript titled “Examining suicide literacy among emerging adults from a medical school in Puerto Rico” for consideration for publication in your upcoming special issue, Self -harm and Suicide: A Global Priority, in Cambridge Prisms: Global Mental Health. The manuscript is 25 pages in length and includes three tables. We respectfully request that it be considered for peer review.

The data presented in this manuscript have not been published previously, and are not under consideration elsewhere. We believe this manuscript is an excellent fit for Cambridge Prisms: Global Mental Health, as it addresses mental health literacy and suicide prevention within the underrepresented population of emerging adults in Puerto Rico. Our findings provide insight into how social and cultural factors shape suicide literacy, which can inform the development of culturally responsive suicide prevention strategies in low- and middle-income settings.

All ethical standards of the American Psychological Association were followed in the conduct of this study, and the research received approval from the Institutional Review Board of Ponce Health Sciences University. My coauthors and I declare that there are no conflicts of interest related to this submission.

I, Fabio Barreto-Ayes, will be serving as the corresponding author. All coauthors listed have reviewed and approved the manuscript and agree with the order of authorship. I will serve as the primary contact with the editorial office and will ensure that all authors remain informed throughout the review and revision process. If the manuscript is accepted, we understand that all coauthors will be required to sign a certification of authorship form.

Thank you for considering our submission. We look forward to the opportunity to contribute to the mission of your journal by advancing understanding of suicide-related knowledge in underrepresented cultural contexts.

Sincerely,

Fabio J. Barreto-Ayes

PhD Clinical Psychology Student

School of Behavioral and Brain Sciences,

Ponce Health Sciences University

fbarreto22@stu.psm.edu

Review: Examining suicide literacy among emerging adult medical students in Puerto Rico — R0/PR2

Conflict of interest statement

Reviewer declares none.

Comments

General Comments:

The manuscript addresses an important and timely topic—the suicide literacy (SL) of emerging adults (EAs), specifically medical students in Puerto Rico. The authors successfully highlight both strengths and limitations in SL among this group. The research is well-grounded in psychiatric literature and contributes valuable insight to suicide prevention efforts within vulnerable populations.

Overall, the manuscript is clearly written, well-referenced, and based on sound methodology. The rationale is well-developed, and the findings are interpreted thoughtfully. There are, however, several areas where additional clarification or elaboration would improve the manuscript, particularly regarding the cultural relevance of the instrument, the interpretation of SL levels, and the implications for psychiatric education.

Title and Abstract:

Consider specifying in the title that the study focuses on medical students. This would more accurately reflect the scope of the sample and avoid the impression that the results generalize to all EAs in Puerto Rico.

The abstract (if included) should more clearly highlight the discrepancy in knowledge across SL domains, especially the low performance on identifying signs and symptoms, which is one of the study’s most important findings.

Introduction:

The introduction provides a comprehensive overview of suicide rates globally and in Puerto Rico, as well as risks specific to emerging adults and medical students. Consider reducing repetitive statistics across populations to improve narrative flow and sharpen the focus on the rationale for the current study.

The conceptual framing of emerging adulthood is well-integrated and supports the study’s focus. It may help to include a brief note on how the developmental features of this stage (e.g., identity exploration, instability) may influence vulnerability to suicidal behavior and/or help-seeking patterns.

The justification for focusing on medical students is clear. However, it may be helpful to elaborate on why third-year students were chosen in particular and whether their stage of training is associated with increased stress or academic burden.

Methods:

The use of a secondary analysis is clearly stated. Please clarify whether participants were excluded for reasons other than age (e.g., incomplete data, survey non-completion), and specify how missing data were handled in descriptive statistics.

While the Literacy of Suicide Scale (LOSS) is a validated tool, the manuscript mentions that it is not culturally adapted for Puerto Rican EAs. Consider expanding on how cultural values might influence responses to specific LOSS items—particularly in the signs and symptoms domain.

Please clarify how the variable “knowing someone with SI/SA” was measured. Was this assessed via a single item? Did participants receive a definition or timeframe (e.g., “in your lifetime,” “in the past year”)?

The procedure section briefly mentions the parent study on mental health stigma. Please clarify whether exposure to stigma-related content occurred before or after participants completed the LOSS questionnaire, as this could influence results.

Results:

The demographic breakdown is well-described. Consider highlighting the notable finding that over 88% of participants had not received any suicide prevention training. This result could be emphasized earlier as it has implications for curriculum development.

The interpretation of the LOSS score as relatively high would benefit from more context. Without established benchmarks for low, moderate, or high SL, please clarify whether there are comparative studies or norms available to justify this interpretation.

The multiple regression analysis is well-conducted and appropriately adjusted for gender. Please consider reporting the model’s R² value to provide readers with a better sense of the variance explained.

In addition to total LOSS scores, the domain-specific findings are important. It may help to further disaggregate the results by domain in both text and tables and briefly describe the types of items participants struggled with, especially in signs and symptoms.

Discussion:

The discussion effectively emphasizes the difference between knowledge of treatment/prevention and the ability to recognize suicidal warning signs. Consider further expanding on why this discrepancy is clinically important, particularly for medical students who may encounter patients in distress during training.

The contact hypothesis is appropriately used to interpret the finding that knowing someone with SI/SA was associated with higher SL. However, as the study is cross-sectional, causal interpretations should be avoided or softened to refer to “association” rather than “effect.”

The discussion of Puerto Rican cultural constructs such as familismo and fatalismo is very valuable. Consider proposing how future studies might operationalize these constructs in relation to SL (e.g., through culturally specific items or qualitative components).

Given that a large proportion of participants had not received suicide prevention training, more concrete recommendations for integrating SL content into medical curricula would be useful. For example, could case-based simulations or peer-led workshops be particularly effective?

Limitations and Future Directions:

The limitations are appropriately acknowledged. Please consider adding the possibility of social desirability bias, especially since stigma remains high around mental health in medical settings.

The manuscript notes that the study did not examine the source of participants' suicide knowledge. Including a recommendation for future studies to explore how SL is acquired (e.g., formal education, lived experience, media) would strengthen this section.

Consider offering suggestions for how the LOSS might be culturally adapted for Puerto Rican or broader Latinx populations. Could culturally grounded constructs be integrated into revised items or subscales?

Another limitation worth noting is that the type and quality of interpersonal contact with someone who had SI/SA was not assessed. The depth of the relationship or frequency of discussion about suicidal thoughts may influence SL in meaningful ways.

The lack of formal SL training among participants is a key finding. Future studies might consider evaluating whether structured workshops or lived-experience panels have measurable effects on SL across specific domains.

Conclusion:

The conclusion is accurate and concise. Consider reiterating the point that SL among medical students is uneven—high in some areas but lacking in others—highlighting a need for targeted education.

You might also emphasize the dual role of medical students as both a vulnerable group and future frontline responders in suicide prevention, reinforcing the urgency of enhancing SL in this population.

Final Recommendation:

This is a well-executed and clearly written manuscript that contributes meaningful insight to psychiatric research on suicide literacy among emerging adults. The findings are both locally relevant and internationally applicable. I recommend minor revisions to improve clarity, address interpretive limitations, and expand the discussion of educational and cultural implications.

Review: Examining suicide literacy among emerging adult medical students in Puerto Rico — R0/PR3

Conflict of interest statement

Reviewer declares none.

Comments

Dear Authors,

Thank you for the opportunity to review this ms on suicide literacy among emerging adult medical students in Puerto Rico. The topic is highly relevant, and the population is clearly of interest, but in its current form the ms has several substantial weaknesses in conceptual framing, analytic interpretation, and methodological transparency that, in my view, need to be addressed before it can make a clear contribution.

First, the conceptual rationale and claimed contribution are not entirely convincing. The introduction does a good job of situating suicide and emerging adulthood, but it remains quite general and does not clearly specify what this study adds beyond existing LOSS-based work with university students and health trainees in other settings. The argument for focusing solely on medical students as “emerging adults” blends developmental theory with professional training concerns, but these strands are not integrated into a coherent conceptual model. As written, it isn’t clear whether the primary contribution is about suicide and developmental stage, professional role, or Puerto Rico–specific context, and the paper tends to overstate novelty.

Second, the use of secondary data from a parent stigma-intervention trial is only minimally described. The ms notes that this is a “cross-sectional secondary analysis of a larger intervention on mental health stigma,” but provides very little information about the parent study. Without this, it’s difficult to assess selection bias and generalizability. The restriction to those aged 21–29 to fit the “emerging adulthood” definition is applied post hoc and is not accompanied by a clear analytic justification or sensitivity check. More detail on the parent trial and a clearer discussion of how this subsample was derived are essential.

Third, the analytic framing and interpretation of results need to be more modest. The multiple linear regression model explains only a very small proportion of variance in suicide literacy (R² = 0.071, adjusted R² = 0.052), yet the discussion treats “knowing someone with SI/SA” as a robust and substantively important predictor. Given that the outcome is influenced by many factors (personal history, prior training, curriculum content, stigma, etc.), the current model is obviously underspecified; the possibility of omitted-variable bias should be explicitly acknowledged. In addition, the key predictor—knowing someone with SI/SA—is dichotomous and does not distinguish type of relationship, closeness, recency, or context of the contact, although the discussion itself emphasizes that such nuances may matter. The ms needs to tone down causal or mechanistic language and present this association as preliminary and modest.

Fourth, the repeated claim that participants have “high” suicide literacy is not empirically supported by the measurement properties of the LOSS. The authors correctly note that the LOSS has no established cut-offs, yet they still interpret a mean of 19.25/27 (71.3%) as “high” literacy and build much of the discussion around this assertion. At the same time, performance in the “signs and symptoms” domain is strikingly low (around 43–44% correct), which contradicts any simple characterization of literacy as globally high. In the absence of validated thresholds, the results should be described more cautiously (e.g., “higher relative performance in treatment/prevention and lower in signs/symptoms”) and framed as a profile of strengths and weaknesses rather than as evidence of overall “high literacy.”

Fifth, some of the cultural explanations advanced in the discussion are speculative and not grounded in the data presented. The authors invoke familismo, fatalismo, and cultural silence around suicide to explain deficits in symptom recognition, but the study did not measure these constructs, nor did it collect qualitative data on how participants interpret suicide-related signs. These are reasonable hypotheses, and the cited literature is relevant, but they should be clearly labeled as conjectural and framed as directions for future research rather than as explanations for the observed pattern of scores in this specific sample.

Sixth, the description of methods and sample characteristics requires more transparency. Recruitment is described only as students “invited by research assistants,” with no information on how many were approached, how many refused, or whether there were systematic differences between participants and non-participants. The extent and pattern of missing data are not reported, yet listwise deletion is used without justification or sensitivity analysis. Reliability of the LOSS in this sample is not reported (only prior alpha values from other studies are cited), which is a simple but important piece of information for a psychometric outcome. All these omissions make it harder to evaluate internal validity and should be addressed.

Seventh, the discussion is disproportionately long and ambitious relative to the simplicity of the design and modesty of the findings. The paper moves quickly from a small cross-sectional study at a single medical school to broader claims about curricular gaps, stigma among medical professionals, and the value of co-produced training with people with lived experience. While the cited literature supports the importance of these issues, the present data provide limited leverage on them. I’d strongly recommend tightening the discussion, focusing on what this dataset can demonstrate (profile of LOSS domains in this sample; modest association of contact with SI/SA and scores), and clearly separating evidence from advocacy and hypothesis.

In terms minor issues, the ms would benefit from careful editing for concision and consistency. There is some repetition between the introduction and discussion, and some sentences are unnecessarily long or redundant. The terminology used to refer to suicidal behaviors and experiences (SI, SA, “suicide behavior,” “suicide mortality,” “lived experience of SI/SA”) could be standardized for clarity. Tables need small clarifications: for example, in Table 2 it should be explicit whether the values in the “M” column are raw scores or percentages, and the labelling should be consistent with how the text describes them. The references contain at least one apparent duplication (Duarté-Vélez et al. 2017/2018) and some minor formatting inconsistencies that should be corrected. Finally, the ethical section could briefly mention data handling/confidentiality procedures, and the methods should explicitly confirm that all measures used in this analysis were collected pre-intervention.

Recommendation: Examining suicide literacy among emerging adult medical students in Puerto Rico — R0/PR4

Comments

Thank you, please see and address the reviewers‘ comments. Mine are included within the reviewers’ comments.

Decision: Examining suicide literacy among emerging adult medical students in Puerto Rico — R0/PR5

Comments

No accompanying comment.

Author comment: Examining suicide literacy among emerging adult medical students in Puerto Rico — R1/PR6

Comments

August 31, 2025

Editor-in-Chief

Cambridge Prisms: Global Mental Health

Cambridge University Press

Dear Editor,

Please find enclosed our manuscript titled “Examining suicide literacy among emerging adults from a medical school in Puerto Rico” for consideration for publication in your upcoming special issue, Self -harm and Suicide: A Global Priority, in Cambridge Prisms: Global Mental Health. The manuscript is 28 pages in length and includes three tables. We respectfully request that it be considered for peer review publication.

The data presented in this manuscript have not been published previously, nor are they under consideration elsewhere. We believe this manuscript is an excellent fit for Cambridge Prisms: Global Mental Health, as it addresses mental health literacy and suicide prevention within the underrepresented population of emerging adults in Puerto Rico. Our findings provide insight into how social and cultural factors shape suicide literacy, which can inform the development of culturally responsive suicide prevention strategies in low- and middle-income settings.

All ethical standards of the American Psychological Association were followed in the conduct of this study, and the research received approval from the Institutional Review Board of Ponce Health Sciences University. My coauthors and I declare that there are no conflicts of interest related to this submission.

I, Fabio Barreto-Ayes, will be serving as the corresponding author. All coauthors listed have reviewed and approved the manuscript and agree with the order of authorship. I will serve as the primary contact with the editorial office and will ensure that all authors remain informed throughout the review and revision process. If the manuscript is accepted, we understand that all coauthors will be required to sign a certification of authorship form.

Thank you for considering our submission. We look forward to the opportunity to contribute to the mission of your journal by advancing understanding of suicide-related knowledge in underrepresented cultural contexts.

Sincerely,

Fabio J. Barreto-Ayes

PhD Clinical Psychology Student

School of Behavioral and Brain Sciences,

Ponce Health Sciences University

fbarreto22@stu.psm.edu

Review: Examining suicide literacy among emerging adult medical students in Puerto Rico — R1/PR7

Conflict of interest statement

Reviewer declares none.

Comments

Thanks for addressing concerns

Recommendation: Examining suicide literacy among emerging adult medical students in Puerto Rico — R1/PR8

Comments

Thanks for addressing the reviewers' concerns.

Decision: Examining suicide literacy among emerging adult medical students in Puerto Rico — R1/PR9

Comments

No accompanying comment.