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Intranasal Helicobacter pylori infection in patients with chronic rhinosinusitis with polyposis

Published online by Cambridge University Press:  03 August 2018

N Siupsinskiene ,
I Katutiene ,
V Jonikiene ,
D Janciauskas  and
S Vaitkus
N Siupsinskiene*
Affiliation:
Faculty of Health Sciences, Klaipeda University, Lithuania Department of Otolaryngology, Academy of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania
I Katutiene
Affiliation:
Department of ENT, Klaipeda Republic Hospital, Lithuania
V Jonikiene
Affiliation:
Department of ENT, Klaipeda Republic Hospital, Lithuania
D Janciauskas
Affiliation:
Department of Pathologic Anatomy, Academy of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania
S Vaitkus
Affiliation:
Department of Otolaryngology, Academy of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania
*
Author for correspondence: Habil. Dr Nora Siupsinskiene, Department of Otolaryngology, Academy of Medicine, Lithuanian University of Health Sciences, Eiveniu 2, Kaunas LT-50009, Lithuania E-mail: norai_s@yahoo.com Fax: +370 37 326862
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Abstract

Objective

To determine the prevalence of Helicobacter pylori infection in nasal biopsy specimens from patients with chronic rhinosinusitis with polyposis versus control patients, and to assess the correlations between H pylori infection identified in the nasal tissue and patients’ sociodemographic data and reflux-related symptoms and signs.

Methods

Nasal biopsy samples were taken from 75 adult patients who underwent nasal surgery for chronic rhinosinusitis with polyposis (clinical group, n = 45) and a deviated septum (control group, n = 30). H pylori infection was identified using histochemical and rapid urease tests.

Results

The prevalence of intranasal H pylori infection was significantly higher in the clinical group (28.9 per cent) compared to the control group (3.3 per cent) (p = 0.005). A significant yet weak association was found between positive H pylori status and laryngopharyngeal reflux related hypertrophy of the posterior commissure of the larynx. No other correlations reached statistical significance.

Conclusion

H pylori infection is potentially related to chronic rhinosinusitis with polyposis. Further research is needed to clarify the role of H pylori as a risk factor for the development of sinonasal diseases and to examine its link with laryngopharyngeal reflux.

Keywords

Helicobacter PyloriSinusitisNasal PolypsLaryngopharyngeal Reflux
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 9 , September 2018 , pp. 816 - 821
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Habil. Dr N Siupsinskiene takes responsibility for the integrity of the content of the paper

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