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True mailgnant mixed tumour of a minor salivary gland

Published online by Cambridge University Press:  29 June 2007

S. C. Toynton ,
M. J. Wilkins ,
H. T. Cook  and
N. D. S. Stafford
S. C. Toynton*
Affiliation:
Department of Otolaryngology, St. Mary's Hospital, Praed Street, London W2 1NY.
M. J. Wilkins
Affiliation:
Department of Histopathology, St. Mary's Hospital, Praed Street, London W2 1NY.
H. T. Cook
Affiliation:
Department of Histopathology, St. Mary's Hospital, Praed Street, London W2 1NY.
N. D. S. Stafford
Affiliation:
Department of Otolaryngology, St. Mary's Hospital, Praed Street, London W2 1NY.
*
Mr S. C. Toynton, Senior Registrar, Department of Otolaryngology, Norfolk and Norwich Hospital, Norwich, Norfolk NR1 3SR.
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Abstract

True malignant mixed tumours (carcinosarcomas) of salivary gland origin are rare and not widely recognized lesions. These tumours account for approximately 0.2 per cent of all malignancies of the major salivary glands (Stephen et al., 1986). They usually occur in pre-existing pleomorphic ademonas of major salivary glands and have an aggressive and often rapidly fatal progression.

We report a case of carcinosarcoma in a minor salivary gland of the upper lip. Its management and the use of immunocy-tochemical stains to demonstrate the separate epithelial and connective issue components are discussed.

Keywords

Salivary gland neoplasmsMixed salivary gland tumourCarcinosarcomaLip neoplasms

Information

Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 1 , January 1994 , pp. 76 - 79
Copyright
Copyright © JLO (1984) Limited 1994

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References

Chen, K. T. K., Weinberg, R. A., Moseley, D. (1984) Carcinosarcoma of the salivary gland. American Journal of Otolaryngology 5: 415–17.CrossRefGoogle Scholar
Garner, S. L., Maves, M. D., Robinson, R. A., Barnes, C. H. (1989) Salivary gland carcinosarcoma: true malignant mixed tumour. Annals of Otology, Rhinology and Larynogology 98: 611–614.CrossRefGoogle Scholar
Hellquist, H., Michaels, L. (1986) Malignant mixed tumour. A salivary gland tumour showing both carcinomatous and sacromatous features. Virchows Archives (Pathology and Anatomy) 409: 93–103CrossRefGoogle Scholar
Spiro, R. H., Huvos, A. G., Strong, E. W. (1977) Malignant mixed tumour of salivary origin. Cancer 39: 388–3963.0.CO;2-D>CrossRefGoogle ScholarPubMed
Stead, R. H., Qizilbash, A. H., Kontozoglou, T., Daya, A. D., Riddell, R. H. (1988) An immunohistochemical study of pleomorphic adenoma of the salivary gland: glial fibrillary acidic protein-like immunoreactivity identifies a major myoepithelial component. Human Pathology 19(1): 32–40CrossRefGoogle Scholar
Stephen, J., Batsakis, J. G., Luna, M. A., von der qweHeyden, U., Byers, R. M. (1986) True malignant mixed tumours (carcinosarcoma) of salivary glands. Oral Surgery, Oral Medicine and Oral Pathology 61: 597–602CrossRefGoogle ScholarPubMed
Tortoledo, M. E., Luna, M. A., Batsakis, J. G. (1984) Carcinomas ex-pleomorphic adenoma and malignant mixed tumours. Archives of Otolaryngology 110: 172–176CrossRefGoogle Scholar