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Depression in Ménière's disease: a systematic review and meta-analysis

Published online by Cambridge University Press:  17 April 2020

J J Patel*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
D A Levy
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, Charleston, USA Frank H Netter MD School of Medicine at Quinnipiac University, North Haven, Connecticut, USA
S A Nguyen
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
H G Rizk
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
T A Meyer
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
*
Author for correspondence: Dr Jaimin J Patel, Department of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC29425, USA E-mail: pateljai@musc.edu

Abstract

Background

Ménière's disease is a debilitating chronic peripheral vestibular disorder associated with psychiatric co-morbidities, notably depression.

Methods

Database searches were performed to identify studies that assessed depression in Ménière's disease. Metrics used to diagnose depression were extracted, along with the prevalence of depression in each study.

Results

Fifteen studies from 8 different countries reported on 6587 patients. The weighted average age was 55.3 years (range, 21–88 years). Depression was measured by eight different scales, with Zung's Self-Rating Depression Scale used most often. A weighted proportion of 45.9 per cent of patients (confidence interval = 28.9–63.3) were depressed. Weighted averages (± standard deviations) of Beck's Depression Inventory and the Illness Behavior Questionnaire – Dysphoria were 8.5 ± 7.9 and 2.4 ± 1.7, respectively.

Conclusion

The prevalence of depression in patients with Ménière's disease is nearly 50 per cent. Treating otolaryngologists should have a low threshold to screen and refer appropriately. Identifying and treating depression should allow for improvement of overall quality of life in patients with Ménière's disease.

Type
Review Articles
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Dr J J Patel takes responsibility for the integrity of the content of the paper

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