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Mesenchymal cell atypicality in inflammatory polyps

Published online by Cambridge University Press:  29 June 2007

Bruce H. Klenoff  and
Max L. Goodman
Bruce H. Klenoff
Affiliation:
Boston, Mass.
Max L. Goodman
Affiliation:
Massachusetts Eye and Ear Infirmary, 243 Charles St., Boston, Massachusetts 02114, U.S.A.
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Abstract

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Excised nasal polyps should be examined histologically for classification as to aetiological process. Recently a ‘pseudosarcomatous’ change was reported in nasal polyps. We reviewed one hundred excised polyps for mesenchymal atypicality and found a wide degree of mesenchymal atypicality in the majority of nasal polyps.

Nasal and choanal inflammatory polyps are the most frequent nasal masses which the otolaryngologist has to treat. Surgical excision is frequently required to alleviate the nasal symptoms of polyps unresponsive to medical therapy. Excised nasal polyps should be examined histologically for classification as to possible aetiological mechanisms and to rule out neoplastic lesions (Shea, 1947).

Smith, Echevarria, and McLelland (Smith, 1974) recently described ‘pseudosarcomatous changes’ in nasal polyps. This stimulated us to investigate our inflammatoru nasal polyps for these histological changes. Casual observations demonstrated an impressive number of inflammatory polyps with varying amounts of atypical mesenchymal stroma cells. To quantitate these alterations, we reviewed the histological slides from one hundred patients with excised inflammatory polyps and the results are the subject of this report.

Information

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 91 , Issue 9 , September 1977 , pp. 751 - 756
Copyright
Copyright © JLO (1984) Limited 1977

References

REFERENCES

Ash, J. E., Beck, M. R., and Wilkes, J. D. (1964). Tumors of Upper Respiratory Tract and Ear. Washington, D.C., Armed Forces Institute of Pathology F12–188.Google Scholar
Ash, J. E., and Raum, M. (1956) Atlas of Otolaryngic Pathology. Washington, D.C., Armed Forces Institute of Pathology, p. 159.Google Scholar
Berdal, P. (1954) Acta Oto-Laryngologica, 115, 7.Google Scholar
Blumsteix, G. I. (1966) Archives of Otolaryngology, 83, 226.Google Scholar
Compagxo, J., Hyams, V. J., and Lepore, M. L. (1976) Archives of Pathology and Laboratory Medicine, 100, 224.Google Scholar
Davidson, F. W. (1953). Annals of Otology Rhinology and Laryngology, 62, 412.CrossRefGoogle Scholar
Dolowitz, P. A., and Dougherty, T. F. (1961). Archives of Otolaryngology, 74, 63.Google Scholar
Ross, R., and Odlaxd, G. (1968). The Journal of Cell Biology, 39, 152.CrossRefGoogle Scholar
Samter, M. (1961). Archives of Otolaryngology, 73, 334.CrossRefGoogle Scholar
Samter, M. (1973) Hospital Practice, 8, 85.CrossRefGoogle Scholar
Semenov, H. (1952) Transactions of American Academy of Ophthalmology and Otolaryngology, 56, 121.Google Scholar
Shea, J. (1947). Annals of Otology, Rhinology and Laryngology, 56, 1029.CrossRefGoogle Scholar
Smith, C. J. (1974). Archives of Otolaryngology, 99, 228.CrossRefGoogle Scholar
Smith, P. S. (1971). The Laryngoscope, 81, 636.CrossRefGoogle Scholar
Taylor, M. (1963) The Journal of Laryngology and Otology, 77, 326.CrossRefGoogle Scholar
Weille, F. L., and Gohd, R. S. (1956) The Annals of Otology, Rhinology and Laryngology, 65, 443.CrossRefGoogle Scholar
Weisskopf, A., and Burn, H. (1959). Transactions of American Laryngological Association, 80, 236.Google Scholar