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Nosocomial Acquisition of Pertussis Diagnosed by Polymerase Chain Reaction

Published online by Cambridge University Press:  02 January 2015

Anne G. Matlow ,
Sue Nelson ,
Rick Wray  and
Peter Cox
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Abstract

Awareness is growing of the role of pertussis infection among adolescents and adults, and of the possibility of nosocomial transmission. However, pertussis remains difficult to diagnose. We report a case of nosocomially acquired pertussis in a healthcare worker, diagnosed by polymerase chain reaction. The high sensitivity and rapid turnaround time for this test is useful to confirm the diagnosis when advising a healthcare worker to refrain from working.

Information

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 18 , Issue 10 , October 1997 , pp. 715 - 716
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1997 

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References

1. Hallander, HO, Storsaeter, J, Mollby, R. Evaluation of serology and nasopharyngeal cultures for diagnosis of pertussis in a vaccine efficacy trial. J Infect Dis 1991;163:1046–1054.Google Scholar
2. Reizenstein, E, Johansson, B, Mardin, L, Abens, J, Mollby, R, Hallander, HO. Diagnostic evaluation of polymerase chain reaction discriminative for Bordetella pertussis, B parapertussis and B bronchiseptica . Diagn Microbiol Infect Dis 1993;17:185–191.Google Scholar
3. van der Zee, A, Agterberg, C, Peeters, M, Schellekens, J, Mooi, F. Polymerase chain reaction assay for pertussis: simultaneous detection and discrimination of Bordetella pertussis and Bordetella parapertussis . J Clin Microbiol 1993;31:2134–2140.Google Scholar
4. Glare, E, Paton, J, Premier, R, Lawrence, A, Nisbet, I. Analysis of a repetitive DNA sequence from Bordetella pertussis and its application to the diagnosis of pertussis using the polymerase chain reaction. J Clin Microbiol 1990;28:1982–1987.Google Scholar
5. Grimpel, E, Begue, P, Anjak, I, Betsou, F, Guiso, N. Comparison of polymerase chain reaction, culture and Western immunoblot serology for diagnosis of Bordetella pertussis infection. J Clin Microbiol 1993;31:2745–2750.Google Scholar
6. He, Q, Mertsola, J, Soini, H, Viljanen, MK. Sensitive and specific polymerase chain reaction assays for detection of Bordetella pertussis in nasopharyngeal specimens. J Pediatr 1994; 124:421–426.Google Scholar
7. He, Q, Mertsola, J, Soini, H, Skurnik, M, Ruuskanen, O, Viljanen, M. Comparison of polymerase chain reaction with culture and enzyme immunoassay for diagnosis of pertussis. J Clin Microbiol 1993;31:642–645.Google Scholar
8. Nelson, S, Matlow, A, McDowell, C, et al. Detection of Bordetella pertussis in clinical specimens using the polymerase chain reaction and a micro titre-based DNA hybridization assay. J Clin Microbiol 1997;35:642–645.Google Scholar
9. McLafferty, M, Harcus, D, Hewlett, E. Nucleotide sequence and characterization of a repetitive DNA element from the genome of Bordetella pertussis with characteristics of an insertion sequence. J Gen Microbiol 1988;134:2297–2306.Google Scholar
10. Steketee, RW, Wassilak, GF, Adkins, WN Jr, et al. Evidence for a high attack rate and efficacy of erythromycin prophylaxis in a pertussis outbreak in a facility for the developmentally disabled. J Infect Dis 1988;157:434–440.Google Scholar
11. Fisher, MC, Long, SS, McGowan, KL, Kaselis, E, Smith, DG. Outbreak of pertussis in a residential facility for handicapped people. J Pediatr 1989;114:934–939.Google Scholar
12. Kurt, TL, Yeager, AS, Guenette, S, Dunlop, S. Spread of pertussis by hospital staff. JAMA 1972;221:264–267.Google Scholar
13. Committee on Infectious Diseases. Red Book. Elk Grove Village, IL: American Academy of Pediatrics; 1994:355–367.Google Scholar
14. Weber, DJ, Rutala, WA. Management of health care workers exposed to pertussis. Infect Control Hosp Epidemiol 1994;15:411–415.Google Scholar