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MECHANISMS OF ANEUPLOIDY INDUCTION IN HUMAN OOGENESIS AND EARLY EMBRYOGENESIS

Published online by Cambridge University Press:  01 May 2007

JOY D A DELHANTY*
Affiliation:
UCL Centre for Preimplantation Genetic Diagnosis, Institute of Women's Health, University College London.
*
UCL Centre for Preimplantation Genetic Diagnosis, Institute of Women's Health, University College London, 86–96 Chenies Mews, London WC1E 6HX, United Kingdom.

Extract

Reproductive failure is relatively common in humans compared with other mammalian species that have been studied. In young couples that are trying to conceive, the fecundity rate, (probability of achieving a clinically recognised pregnancy within a monthly cycle) is about 25%. The major cause of implantation failure in humans after both in vivo and in vitro fertilisation is now thought to be the high incidence of chromosomal abnormality.

Information

Type
Research Article
Copyright
Copyright © Cambridge University Press 2007

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