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Multi-institutional perspectives on team science evaluation in clinical and translational science programs: Practices, challenges, facilitators, and future directions

Published online by Cambridge University Press:  31 March 2026

Whitney A. Sweeney*
Affiliation:
Institute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA
Joe Hunt
Affiliation:
Indiana Clinical and Translational Sciences Institute, Indianapolis, IN, USA Indiana University School of Medicine, Indianapolis, IN, USA
Tammy J. Sajdyk
Affiliation:
Indiana Clinical and Translational Sciences Institute, Indianapolis, IN, USA Indiana University School of Medicine, Indianapolis, IN, USA
Boris Volkov
Affiliation:
Clinical and Translational Science Institute and Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA
*
Corresponding author: W. A. Sweeney; Email: wasweeney@wisc.edu.
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Abstract

Team science is central to clinical and translational research; however, systematic evaluation of collaborative efforts remains inconsistent and underdeveloped. To better understand current team science evaluation practices within clinical and translational science programs, we conducted a structured cross-sectional survey of team science and evaluation professionals. We analyzed quantitative data using descriptive statistics and qualitative responses through thematic analysis. Among participating organizations, the majority have implemented team science evaluations, predominantly using mixed-methods approaches combining quantitative metrics and qualitative assessments. Evaluation findings were primarily used to inform programing, improve team functioning, and secure funding. Reported challenges fell into four key areas: methodology; implementation; data analysis; and organization. Facilitators included: methodological enhancements, organizational support, collaborative approaches, and infrastructure elements. Participants emphasized using interim measures (e.g., team dynamics and satisfaction) that move beyond traditional outcome measures so that evaluations better reflect how teams interact, adapt, and progress as they develop. While team science evaluation adoption is substantial among leading translational research institutions, significant methodological gaps persist. Future directions focus on developing standardized frameworks with local flexibility, creating validated instruments, utilizing interim process measures, and demonstrating return on investment (ROI) to advance both evaluation science and translational outcomes.

Information

Type
Special Communication
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2026. Published by Cambridge University Press on behalf of Association for Clinical and Translational Science
Figure 0

Figure 1. Team science evaluation approaches across clinical and translational science programs. This sample includes the 24 respondents who indicated that team science evaluation was conducted at their institution.

Figure 1

Figure 2. Application of evaluation findings across clinical and translational science programs. This sample includes the 24 respondents who indicated that team science evaluation was conducted at their institution.

Figure 2

Table 1. Summary of the insights from the multi-institutional survey on team science evaluation challenges, facilitators, measures, and future directions

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