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Fine-needle aspiration cytology of submandibular gland lesions

Published online by Cambridge University Press:  29 June 2007

Timo Atula ,
Reidar Grénman ,
Pekka Laippala  and
Pekka-Juhani Klemi
Timo Atula*
Affiliation:
Department of Otorhinolaryngology, Turku University Central Hospital
Reidar Grénman
Affiliation:
Department of Otorhinolaryngology, Turku University Central Hospital
Pekka Laippala
Affiliation:
Department of public Health/Biometry Unit, University of Tampere, Finland.
Pekka-Juhani Klemi
Affiliation:
Department of Pathology, Turku University Central Hospital
*
Dr Timo Atula, Department of Otorhinolaryngology, university of Turky, Fin-20520, Turku, Finland.
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Abstract

The usefulness of fine-needle aspiration cytology (FNAC) in the diagnosis and treatment of submandibular gland lesions is not well known. The 210 FNACs taken from submandibular gland lesions at Turku University Central Hospital between 1984 and 1991 were reviewed. Of these FNACs, 78 samples from primary lesions were confirmed histologically. Within this subset 10 FNACs were taken from benign neoplasms, all of which were correctly classified (sensitivity 100 per cent; specificity 88 percent). Only four of the 14 FNACs from malignant lesions were cytologically considered malignant (sensitivity 29 per cent). On the other hand, four FNACs raised a false suspicion of malignancy (specificity 6 per cent). Out of 54 FNACs from non-neoplastic lesions 43 were correct (sensitivity 80 per cent; specificity 63 per cent). There were 104 patients (123 FNACs), who had not been operated on: the follow-up of these patients shows that in this subset of FNACs there were no false malignant but probably one false benign finding (1 per cent). We conclude that FNAC can offer valuable information about the type of the submandibular gland lesion, but the decision of operative and other treatment should not be based solely on the result of FNAC.

Keywords

Biopsy, needleSubmandibular gland diseasesSubmandibular gland neoplasmsCytology

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 9 , September 1995 , pp. 853 - 858
Copyright
Copyright © JLO (1984) Limited 1995

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References

Atula, T., Grénman, R., Laippala, P., Klemi, P.-J. (1995) Fine-needle aspiration in the diagnosis of parotid gland lesions: evaluation of 438 biopsies. Diagnostic Cytopathology (in Press).3.0.CO;2-G>CrossRefGoogle Scholar
Baatenburg de Jong, R. J., Rongen, R. J., Verwoerd, C. D. A., van Overhagen, H., Lameris, J. S., Knegt, P. (1991) Ultrasound-guided fine-needle aspiration biopsy of neck nodes. Archives of Otolaryngology, Head and Neck Surgery 117: 402–404.CrossRefGoogle ScholarPubMed
Batsakis, J. G., Sneige, N., El-Naggar, A. (1992) Fine-needle aspiration of salivary glands: its utility and tissue effects. Annals of Otology, Rhinology and Laryngology 101: 185–188.CrossRefGoogle ScholarPubMed
Cohen, M. B., Ljung, B.-M. E., Boles, R. (1986) Salivary gland tumors. Fine-needle aspiration versus frozen-section diagnosis. Archives of Otolaryngology, Head and Neck Surgery 112: 867–869.CrossRefGoogle Scholar
Cross, D. L., Gansler, T. S., Morris, R. C. (1990) Fine-needle aspiration and frozen section of salivary gland lesions. Southern Medical Journal 83: 283–286.CrossRefGoogle ScholarPubMed
Eneroth, C.-M., Zajicek, J. (1966) Aspiration biopsy of salivary gland tumors. III: Morphological studies on smears and histologic sections from 368 mixed tumors. Acta Cytologica 10: 440–454.Google Scholar
Eneroth, C.-M., Franzen, S., Zajicek, J. (1967) Cytologic diagnosis on aspirate from 1000 salivary gland tumours. Acta Otolaryngologica 224: 168–171.CrossRefGoogle Scholar
Frable, M. A. S., Frable, W. J. (1991) Fine-needle aspiration biopsy of salivary glands. Laryngoscope 101: 245–249.CrossRefGoogle ScholarPubMed
Kern, S. B. (1988) Necrosis of a Warthin's tumor following fine-needle aspiration. Acta Cytologica 32: 207–208.Google ScholarPubMed
Lau, T., Balle, V. H., Bretlau, P. (1986) Fine-needle aspiration biopsy in salivary gland tumours. Clinical Otolaryngology 11: 75–77.CrossRefGoogle ScholarPubMed
Layfield, L. J., Glasgow, B. J. (1991) Diagnosis of salivary gland tumors by fine-needle aspiration cytology: a review of clinical utility and pitfalls. Diagnostic Cytopathology 7: 267–272.CrossRefGoogle ScholarPubMed
Layfield, L. J., Tan, P., Glasgow, B. J. (1987) Fine-needle aspiration of salivary gland lesions. Comparison with frozen sections and histologic findings. Archives of Pathology and Laboratory Medicine 111: 346–353.Google ScholarPubMed
Lindberg, L. G., Åkerman, M. (1976) Aspiration cytology of salivary gland tumors: diagnostic experience from six years of routine laboratory work. Laryngoscope 86: 584–594.CrossRefGoogle ScholarPubMed
Mavec, P., Eneroth, C.-M., Franzen, S., Moberger, G., Zajicek, J. (1964) Aspiration biopsy of salivary gland tumors. I: Correlation of cytologic reports from 652 aspiration biopsies with clinical and histologic findings. Acta Otolaryngologica 58: 471–484.CrossRefGoogle ScholarPubMed
Nettle, W. J. S., Orell, S. R. (1989) Fine-needle aspiration in the diagnosis of salivary gland lesions. Australian and New Zealand Journal of Surgery 59: 47–51.CrossRefGoogle ScholarPubMed
O'Dwyer, P., Farrar, W. B., James, A. G., Finkelmeier, W., McCabe, D. P. (1986) Needle aspiration biopsy of major salivary gland tumors: its value. Cancer 57: 554–557.3.0.CO;2-G>CrossRefGoogle ScholarPubMed
Orell, S. R., Nettle, W. J. S. (1988) Fine-needle aspiration biopsy of salivary gland tumours: problems and pitfalls. Pathology 20: 332–337.CrossRefGoogle ScholarPubMed
Persson, P. S., Zettergren, L. (1973) Cytologic diagnosis of salivary gland tumors by aspiration biopsy. Acta Cytologica 17: 351–354.Google ScholarPubMed
Pitts, D. B., Hilsinger, R. L., Karandy, E., Ross, J. C., Caro, J. E. (1992) Fine-needle aspiration in the diagnosis of salivaryn gland disorders in the community hospital setting. Archives of Otolaryngology, Head and Neck Surgery 118: 479–482.CrossRefGoogle ScholarPubMed
Qizilbash, A. H., Sianos, J., Young, J. E. M., Archibald, S. D. (1985) Fine-needle aspiration biopsy cytology of major salivary glands. Acta Cytologica 29: 503–512.Google ScholarPubMed
Rodriguez, H. P., Silver, C. E., Moisa, I. I., Chancho, M. S. (1989) Fine-needle aspiration of parotid tumors. American Journal of Surgery 158: 342–344.CrossRefGoogle ScholarPubMed
Sismanis, A., Merriam, J. M., Kline, T. S., Davis, R. K., Shapsay, S. M., Strong, M. S. (1981) Diagnosis of salivary gland tumors by fine-needle aspiration biopsy. Head and Neck Surgery 3: 482–489.CrossRefGoogle ScholarPubMed
Smith, E. H. (1984) The hazards of fine-needle aspiration biopsy. Ultrasound in Medicine and Biology 10: 629–634.CrossRefGoogle ScholarPubMed
Webb, A. J. (1973) Cytologic diagnosis of salivary gland lesions in adult and pediatric surgical patients. Acta Cytologica 17: 51–58.Google ScholarPubMed
Weinberger, M. S., Rosenberg, W. W., Meurer, W. T., Robbins, K. T. (1992) Fine-needle aspiration of parotid gland lesions. Head and Neck 14: 483–487.CrossRefGoogle ScholarPubMed
Weiss, M. H., Kisiel, D. L., Bhatia, P. (1990) Predictive value of brain stem-evoked response in the diagnosis of acoustic neuroma. Archives of Otolaryngology, Head and Neck Surgery 103: 583–585.CrossRefGoogle Scholar
Young, J. (1989) Fine needle aspiration cytology of salivary glands. Ear, Nose adn Throat Journal 68: 120–129.Google ScholarPubMed
Young, J. A., Smallman, L. A., Thompson, H., Proops, D. W., Johnson, A. P. (1990) Fine-needle aspiration cytology of salivary gland lessions. Cytopathology 1: 25–33.CrossRefGoogle Scholar
Zurrida, S., Alassio, L., Taradati, N., Bartoli, C., Chiesa, F., Pilottis, S. (1993) Fine-needle aspiration of parotid masses. Cancer 72: 2306–2311.3.0.CO;2-E>CrossRefGoogle ScholarPubMed