Collectively known as the alloimmune cytopenias, hemolytic disease of the fetus and newborn, alloimmune thrombocytopenia and alloimmune neutropenia are all consequences of maternal immunisation to fetal blood cells. The effective prevention, diagnosis and management of these disorders has become a team effort involving haematologists, obstetricians, paediatricians, immunologists, laboratory technicians, midwives and research scientists. This book has been written by experts in their respective fields to bring together the issues of pathogenesis, epidemiology, prevention, diagnosis and clinical management. This comprehensive but accessible account is extensively cross-referenced to emphasise the links between pathogenesis and clinical sequelae, between epidemiology and the rationale for screening programmes, and between diagnosis and therapeutic intervention. This is an authoritative overview suitable for trainees in obstetrics, materno-fetal medicine, transfusion medicine and clinical immunology.

"This book serves as an excellent update on the comprehensive management of alloimmune disorders of pregnancy. It is an excellent source..." Canadian Journal of Medical Laboratory Science

"[V]ery useful in understanding the mechanisms of the alloimmune response...I do not know of any other book that covers this topic." Doody's Review Service G

"This book will serve as a useful resource for the many participants in multidisciplinary teams that manage alloimmune disorders in pregnancy. It should serve to enhance communication and coordination among investigators and clinical specialists in each of the contributing fields, thus achieving the editors' goals." The New England Journal of Medicine