An Introduction to Vascular Biology: From Basic Science to Clinical Practice

doi:10.1017/CBO9780511545948

Vascular biology is an exciting and rapidly advancing area of medical research, with many new and emerging pathophysiological links to an increasing number of diseases. This updated and expanded new edition takes full account of these developments and conveys the basic science underlying a wide range of clinical conditions including atherosclerosis, hypertension, diabetes, and pregnancy. As with the first edition, the publication provides an introductory account of vascular biology before leading on to explain mechanisms involved in disease processes. Other emerging topics include the role of nitric oxide and apoptosis in vascular biology. The breadth and range of subjects covered in this new edition do full justice to this increasingly important area of clinical research and medicine. This multidisciplinary approach will suit the needs of all those seeking to refresh their knowledge with the very latest advances from basic science through to clinical practice.

‘Beverley Hunt and her co-editors have succeeded in putting together a collection of varied chapters in which the underlying structural and functional abnormalities in blood vessels are described scientifically in the context of clinical disorders. Individual chapters are easy to read and should provide helpful guidance to clinicians and those interested in the pathophysiological basis of vascular medicine.’

Source: Journal of the Royal Society of Medicine

Review of first edition‘… it makes excellent reading … for readers who are interested in gaining fundamental understanding of this critical area. I believe the book offers an excellent pathway towards this goal.’

Source: British Journal of Surgery

Review of first edition‘It is well written, with the correct balance of figures, tables and text, and also well referenced … I warmly recommend it.’

Source: Biomedical Sciences

- Aa Reduce text
- Aa Enlarge text

View selected items
Save to my bookmarks
Export citations
Download PDF (zip)
Save to Kindle
Save to Dropbox
Save to Google Drive
Save content to
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to .

To save content items to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Please be advised that item(s) you selected are not available.
You are about to save
Your Kindle email address

Please provide your Kindle email.

@free.kindle.com @kindle.com (service fees apply)

By using this service, you agree that you will only keep content for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services

Contents

Frontmatter
pp i-iv
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Contents
pp v-vi
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

List of contributors
pp vii-xii
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Preface
pp xiii-xiv
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part I - Basic science
pp 1-2
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

1 - Vascular tone
pp 3-32
- By Alun D. Hughes, Clinical Pharmacology, NHLI, Imperial College, St Mary's Hospital, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

2 - Vascular compliance
pp 33-48
- By Brenda A. Kelly, Maternal and Fetal Research Unit/Centre for Cardiovascular and Vascular Biology, King's College, London, Philip Chowienczyk, Department of Clinical Pharmacology, St Thomas' Hospital, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

3 - Flow-mediated responses in the circulation
pp 49-69
- By Lucilla Poston, Department of Obstetrics and Gynaecology, Guy's, King's and St Thomas' School of Medicine, King's College London, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

4 - Neurohumoral regulation of vascular tone
pp 70-92
- By Kirsty M. McCulloch, Department of Pharmacology, Quintiles Ltd, Edinburgh, John C. McGrath, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

5 - Angiogenesis: basic concepts and the application of gene therapy
pp 93-113
- By John W. Quarmby, Alison W. Halliday, Department of Vascular Surgery, St George's Hospital, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

6 - The regulation of vascular smooth muscle cell apoptosis
pp 114-128
- By Nicola J. McCarthy, Martin R. Bennett, Unit of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

7 - Wound healing: laboratory investigation and modulating agents
pp 129-166
- By Nick L. Occleston, Julie T. Daniels, Peng T. Khaw, Department of Pathology, Moorfields Eye Hospital, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part II - Pathophysiology: mechanisms and imaging
pp 167-168
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

8 - Genes for hypertension
pp 169-185
- By Mark Caulfield, Joanne Knight, Suzanne O'Shea, Gerard Gardner, Patricia Munroe, Department of Clinical Pharmacology, St Bartholomew's and The Royal London School of Medicine and Dentistry, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

9 - The endothelium in health and disease
pp 186-215
- By Beverley J. Hunt, Departments of Haematology and Rheumatology, Guy's and St Thomas' Trust, London., Karen M. Jurd, Protection and Performance Department, Centre for Human Sciences, DERA Alverstoke, Gosport
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

10 - Nitric oxide
pp 216-258
- By Norman Chan, Patrick Vallance, Rayne Institute, University College London, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

11 - Magnetic resonance imaging in vascular biology
pp 259-282
- By Alan R. Moody, Department of Academic Radiology, Queens Medical Centre, Nottingham
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part III - Clinical practice
pp 283-284
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

12 - Vascular biology of hypertension
pp 285-301
- By Michael Schachter, Department of Clinical Pharmacology, Imperial College School of Medicine, St Mary's Hospital, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

13 - Atherosclerosis
pp 302-317
- By James H. F. Rudd, Peter L. Weissberg, School of Clinical Medicine, University of Cambridge, Cambridge
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

14 - Abdominal aortic aneurysm
pp 318-326
- By Janet T. Powell, Department of Vascular Surgery, Imperial College School of Medicine, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

15 - The vasculature in diabetes
pp 327-342
- By John E. Tooke, Department of Vascular Medicine, Postgraduate Medical School, Exeter, Kah Lay Goh, Department of Diabetes and Vascular Medicine Research Centre, Royal Devon & Exeter Hospital (Wonford), Exeter, Angela C. Shore, Department of Diabetes and Vascular Medicine Research Centre, Royal Devon & Exeter Hospital (Wonford), Exeter
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

16 - The vasculitides
pp 343-360
- By Peter Hewins, Caroline O. S. Savage, Renal Immunobiology Group, University of Birmingham, Birmingham
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

17 - Pulmonary hypertension
pp 361-380
- By Tim Higenbottam, Clinical Sciences, AstraZeneca R&D Charnwood, Loughborough, Leicestershire, Helen Marriott, Section of Medicine and Pharmacology, Division of Clinical Sciences, Medical School, University of Sheffield, Sheffield
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

18 - Role of endothelial cells in transplant rejection
pp 381-397
- By Marlene L. Rose, Division of Cardiothoracic Surgery, Imperial College School of Medicine, Harefield, Middlesex
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

19 - Vascular function in normal pregnancy and preeclampsia
pp 398-426
- By Lucilla Poston, Department of Obstetrics and Gynaecology, Guy's, King's and St Thomas' School of Medicine, King's College, London, David Williams, Department of Obstetrics and Gynaecology, Imperial College School of Medicine, London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Index
pp 427-458
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Metrics

Altmetric attention score

Total number of HTML views: 0

Total number of PDF views: 0 *

Loading metrics...

Total views: 0 *

Loading metrics...

* Views captured on Cambridge Core between #date#. This data will be updated every 24 hours.

Usage data cannot currently be displayed.

Why this information is here

This section outlines the accessibility features of this content - including support for screen readers, full keyboard navigation and high-contrast display options. This may not be relevant for you.

Accessibility Information

Accessibility compliance for the PDF of this book is currently unknown and may be updated in the future.

An Introduction to Vascular Biology

From Basic Science to Clinical Practice

Book description

Reviews

Refine List

Actions for selected content:

Save Search

Contents

Metrics

Altmetric attention score

Full text views

Book summary page views

Accessibility standard: Unknown

Why this information is here

Accessibility Information