Illustrated Pathology of the Spleen

Bridget S. Wilkins; Dennis H. Wright

doi:10.1017/CBO9780511545979

The major aim of this book is to de-mystify splenic pathology for non-specialist consultants and trainees in histopathology. The interpretation of pathological changes in the human spleen provides a significant challenge to the skills of even the most highly trained histopathologists. This comprehensive account of the most important and frequently encountered pathological conditions affecting the spleen is highly illustrated in colour throughout with numerous detailed macroscopic and microscopic specimens. Emphasis is placed upon the importance of adequate clinical information and technical preparation of splenectomy specimens in obtaining the best possible histopathological assessment of the tissue. A systematic, analytical approach to interpretation of pathological changes is used throughout the book. This should enable readers to feel confident in their assessment of significant processes within the spleen. This volume serves as an illustrated atlas, a bench manual, as a text, and as a source of reference, and will be an indispensable guide.

‘This volume serves as an illustrative atlas, as a bench manual, as a text and as a source of useful selected references … the book will not only be of great value to trainees but will also be useful to experienced consultants and will become an indispensable guide that should be readily available in all libraries and reporting rooms in departments of histopathology.’

Source: Annals of Oncology

‘ Each chapter is generously illustrated throughout, including immunostained text is succinct and consistently aimed at helping in the diagnostic process, including some basic molecular mechanisms … This is a splendid text which will provide help with the surgical pathology of the spleen.’

J. R. Goepel

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Illustrated Pathology of the Spleen

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Contents

Frontmatter
pp i-iv

Contents
pp v-viii

Preface
pp ix-x

Acknowledgements
pp xi-xii

1 - Introduction
pp 1-12

2 - Normal structure, development and functions of the spleen
pp 13-34

3 - Post-traumatic and incidentally removed spleens
pp 35-46

4 - The spleen in hereditary blood cell abnormalities and auto-immune disorders
pp 47-62

5 - The spleen in immunodeficiency and systemic infections
pp 63-76

6 - Lymphomas involving the spleen
pp 77-110

7 - The spleen in myeloproliferative disorders
pp 111-124

8 - Pathology of the splenic stroma
pp 125-150

9 - Metastases and miscellaneous conditions
pp 151-162

10 - Summary: some key points in splenic differential diagnosis
pp 163-180

Index
pp 181-192

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