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  3. Seasonal Patterns of Stress, Immune Function, and Disease
  • Cited by 171
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    • Publisher:
      Cambridge University Press
      Publication date:
      11 November 2009
      25 March 2002
      ISBN:
      9780511546341
      9780521590686
      9780521021173
      DOI:
      https://doi.org/10.1017/CBO9780511546341
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.609kg, 308 Pages
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.474kg, 308 Pages
      • Subjects:
      Endocrinology, Life Sciences, Physiology and Biological Physics, Medicine
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    Subjects:
    Endocrinology, Life Sciences, Physiology and Biological Physics, Medicine
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    Book description

    This book presents evidence that infection is cyclical with the seasons, and that this phenomenon is mirrored in cycles of immune function. The book identifies the mechanisms by which immune systems are bolstered to counteract seasonally-recurrent stressors, such as extreme temperature reductions and food shortages. Stress, infectious diseases, autoimmune diseases, and human cancers are examined, and the role of hormones such as melatonin and glucocorticoids is considered. The book begins with an overview of seasonality, biological rhythms and photoperiodism, and basic immunology, and then discusses seasonal fluctuations in disease prevalence, immune function, and energetics and endocrinology as they relate to immune function. The clinical significance of this issue is also addressed, as such seasonal changes may play an important role in the development and treatment of infections. This first monograph to examine seasonal immune function from an interdisciplinary perspective will serve practitioners as well as advanced undergraduates and graduate students in biology, immunology, human and veterinary medicine, neuroscience, endocrinology, and zoology.

    Reviews

    ‘ … an interesting and rather provocative book. The issues explored in the book are wide-ranging and interdisciplinary, and will appeal to anyone interested in seasonality and health.’

    Source: The Lancet

    ‘… valuable to anyone interested in immune function in wild animals, and also should be of interest to epidemiologists and immunologists attempting to understand patterns of disease prevalence.’

    L. Michael Romero - Tufts University

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