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Antipsychotic therapy and suicide risk in patients with treatment-resistant depression: target trial emulation framework study: commentary, Narita

Published online by Cambridge University Press:  12 September 2025

Zui C. Narita Open the ORCID record for Zui C. Narita [Opens in a new window]
Zui C. Narita*
Affiliation:
Department of Behavioural Medicine, National Institute of Mental Health, National Centre of Neurology and Psychiatry, Tokyo, Japan
*
Email: zuinarita@ncnp.go.jp
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Abstract

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Keywords

Discrete-time hazardinverse probability weightingpooled logistic regressiong-formulaselection bias

Information

Type
Commentary
Information
The British Journal of Psychiatry , Volume 228 , Issue 1 , January 2026 , pp. 78
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Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists

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References

Tsai, DH-T, Yang, AS-H, Wong, Z-X, Chuang, AT-M, Cheng, MC-Y, Shen, C-Y, et al. Antipsychotic therapy and suicide risk in patients with treatment-resistant depression: target trial emulation framework study. Br J Psychiatry 2025; 228: 37–45. Available from: https://doi.org/10.1192/bjp.2024.283.CrossRefGoogle Scholar
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Murray, EJ, Caniglia, EC, Petito, LC. Causal survival analysis: a guide to estimating intention-to-treat and per-protocol effects from randomized clinical trials with non-adherence. Res Methods Med Health Sci 2021; 2: 39–49.Google Scholar
Narita, Z, Shinozaki, T, Goto, A, Hori, H, Kim, Y, Wilcox, HC, et al. Time-varying living arrangements and suicide death in the general population sample: 14-year causal survival analysis via pooled logistic regression. Epidemiol Psychiatr Sci 2024; 33: e30.CrossRefGoogle ScholarPubMed

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