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1 results

  • Intratympanic gentamicin in Ménière's disease: our experience

  • L Pérez Delgado, J Fraile Rodrigo, P Astier Peña
  • Journal:
    The Journal of Laryngology & Otology / Volume 125 / Issue 4 / April 2011
    Published online by Cambridge University Press:
    15 February 2011, pp. 363-369
    Print publication:
    April 2011
  • Aims:

    To analyse intratympanic gentamicin injection as a treatment option in patients with monolateral Ménière's disease resistant to medical treatment.

    Material and methods:

    Longitudinal, prospective, descriptive study of response to gentamicin treatment in 71 patients diagnosed with Ménière's disease and treated medically for more than a year, unsuccessfully. American Academy of Otolaryngology-Head and Neck Surgery criteria were used for diagnosis and follow up.

    Results:

    Complete vertigo control was obtained in 65.6 per cent of patients, and complete or substantial control in 84.37 per cent. Thirteen patients (18.3 per cent) suffered significant hearing loss.

    Conclusion:

    This intratympanic gentamicin injection protocol enabled effective vertigo control in most patients, and represents a good alternative to more aggressive techniques for the treatment of Ménière's disease which does not respond to medical treatment.