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2 results

  • Variability in the timing and outcome of macronuclear assortment in Tetrahymena thermophila

  • J. Wynne McCoy
  • Journal:
    Genetical Research / Volume 34 / Issue 1 / August 1979
    Published online by Cambridge University Press:
    14 April 2009, pp. 57-67
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  • New experimental designs have detected unexpectedly large variations in the time at which macronuclear assortment begins, and in the ratios of the stabilized products. Variation is detected between strains, and, within strains, between conjugating pairs. The Chx locus gave results ranging from late assortment (40–60 fissions) to early assortment with skewed input, indicating the existence of some relation between the parameters of input ratio and time of determination.

  • The functional units of macronuclear assortment in Tetrahymena thermophila

  • J. Wynne McCoy
  • Journal:
    Genetical Research / Volume 34 / Issue 1 / August 1979
    Published online by Cambridge University Press:
    14 April 2009, pp. 47-56
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  • Macronuclei assorting simultaneously for H, Chx, Mpr, and co, and containing only one or two copies of the HD allele produced several combinations of phenotypes at the other loci, instead of only one or two such combinations. It follows that macronuclear subnuclei, if they exist at all, must frequently exchange parts. Models involving somatic recombination, transient subnuclei, or progressive chromosome fragmentation are discussed as possible explanations.